AIMC Topic: Estradiol

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Effect of 17β-estradiol on milk production, hormone secretion, and mammary gland gene expression in dairy cows.

Journal of dairy science
Estradiol inhibits milk production in dairy cows. The present study evaluated the effect of 17β-estradiol (E2) injections on prolactin (PRL) secretion and the mammary gland response to this hormone. Eight mid-lactation cows were used in a crossover d...

Post-partum concentrations of serum progesterone, oestradiol and prolactin in Arabian mares demonstrating normal maternal behaviour and Arabian mares demonstrating foal rejection behaviour.

Veterinary journal (London, England : 1997)
The aim of this prospective study was to investigate possible endocrine components to foal rejection behaviour in post-partum Arabian mares. Arabian mares were divided into two groups based on their maternal behaviour: (1) mares with normal post-part...

Caloric restriction and IGF-I administration promote rabbit fecundity: Possible interrelationships and mechanisms of action.

Theriogenology
The aim of these in vivo and in vitro studies was to examine the influence of caloric restriction (CR), and the administration of insulin-like growth factor (IGF-I), on rabbit fecundity and to understand the interrelationships between CR and IGF-I, a...

Changes in brain ribonuclease (BRB) messenger RNA in granulosa cells (GCs) of dominant vs subordinate ovarian follicles of cattle and the regulation of BRB gene expression in bovine GCs.

Domestic animal endocrinology
Brain ribonuclease (BRB) is a member of the ribonuclease A superfamily that is constitutively expressed in a range of tissues and is the functional homolog of human ribonuclease 1. This study was designed to characterize BRB gene expression in granul...

Neural-Network Scoring Functions Identify Structurally Novel Estrogen-Receptor Ligands.

Journal of chemical information and modeling
The magnitude of the investment required to bring a drug to the market hinders medical progress, requiring hundreds of millions of dollars and years of research and development. Any innovation that improves the efficiency of the drug-discovery proces...

Machine learning reveals sex-specific 17β-estradiol-responsive expression patterns in white perch (Morone americana) plasma proteins.

Proteomics
With growing abundance and awareness of endocrine disrupting compounds (EDCs) in the environment, there is a need for accurate and reliable detection of EDC exposure. Our objective in the present study was to observe differences within and between th...

Effects of xenoestrogens in human M1 and M2 macrophage migration, cytokine release, and estrogen-related signaling pathways.

Environmental toxicology
Bisphenol A (BPA), bis(2-ethylhexyl)phthalate (DEHP) and di(n-butyl)phthalate (DBP) are environmental estrogens that have been associated with a wide range of adverse health outcomes for which inflammation has also been hypothesized as a potentially ...

Evaluating the added value of salivary hormones in the context of menstrual cycle staging: A machine learning approach and app-implementation.

Psychoneuroendocrinology
OBJECTIVE: Salivary hormone assessment is commonly used in menstrual cycle studies, but its validity for accurate menstrual cycle staging has been questioned. In the present study, we explore possibilities and limitations of salivary hormone assessme...