AIMC Topic: Feasibility Studies

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Can We Predict Clinical Pharmacokinetics of Highly Lipophilic Compounds by Integration of Machine Learning or In Vitro Data into Physiologically Based Models? A Feasibility Study Based on 12 Development Compounds.

Molecular pharmaceutics Sep 23, 2022
While high lipophilicity tends to improve potency, its effects on pharmacokinetics (PK) are complex and often unfavorable. To predict clinical PK in early drug discovery, we built human physiologically based PK (PBPK) models integrating either (i) ma...
Solubility Biological Availability Feasibility Studies Models, Biological Pharmacokinetics Humans Computer Simulation Pharmaceutical Preparations Machine Learning
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Feasibility study of deep-learning-based bone suppression incorporated with single-energy material decomposition technique in chest X-rays.

The British journal of radiology Sep 19, 2022
OBJECTIVE: To improve the detection of lung abnormalities in chest X-rays by accurately suppressing overlapping bone structures in the lung area. According to literature on missed lung cancer in chest X-rays, such structures are a significant cause o...
Humans Radiography Feasibility Studies X-Rays Algorithms Deep Learning
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Robot-assisted simple prostatectomy with the novel HUGO™ RAS System: feasibility, setting, and perioperative outcomes.

Minerva urology and nephrology Sep 12, 2022
Robot-assisted simple prostatectomy (RASP) has demonstrated better peri-operative outcomes as compared to open simple prostatectomy. However, RASP is still limited by platform availability and cost-effectiveness issues. The new surgical robots increa...
Aged Male Robotics Humans Feasibility Studies Laparoscopy Prostatectomy Robotic Surgical Procedures
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Preclinical feasibility of robot-assisted sentinel lymph node biopsy using multi-modality magnetic and fluorescence guidance in the head and neck.

Head & neck Sep 8, 2022
BACKGROUND: Sentinel lymph node biopsy (SLNB) is a staging procedure dependent on accurate mapping of draining lymphatics via tracers. Robot-assisted SLNB enables access to multiple neck levels with a single incision and intraoperative fluorescence g...
Indocyanine Green Sentinel Lymph Node Biopsy Animals Fluorescent Dyes Swine Feasibility Studies Lymph Nodes Robotics Fluorescence
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Feasibility and Potential Effects of Robot-Assisted Passive Range of Motion Training in Combination with Conventional Rehabilitation on Hand Function in Patients with Chronic Stroke.

Journal of rehabilitation medicine Aug 26, 2022
OBJECTIVE: To assess the effects of exoskeleton robot-assisted passive range of motion for induction training in combination with conventional hand rehabilitation in patients with chronic stroke.
Humans Feasibility Studies Robotics Range of Motion, Articular Stroke Stroke Rehabilitation Treatment Outcome Recovery of Function Upper Extremity
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Analysis of the feasibility of using deep learning for multiclass classification of dental anomalies on panoramic radiographs.

Dental materials journal Aug 23, 2022
The aim of the feasibility study was to construct deep learning models for the classification of multiple dental anomalies in panoramic radiographs. Panoramic radiographs with single supernumerary teeth and/or odontomas were considered the "case" gro...
Tooth, Supernumerary Deep Learning Odontoma Radiography, Panoramic Humans Feasibility Studies
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Application of an EMG-Rehabilitation Robot in Patients with Post-Coronavirus Fatigue Syndrome (COVID-19)-A Feasibility Study.

International journal of environmental research and public health Aug 20, 2022
This pilot study aimed to assess the safety and feasibility of an EMG-driven rehabilitation robot in patients with Post-Viral Fatigue (PVF) syndrome after COVID-19. The participants were randomly assigned to two groups (IG-intervention group and CG-c...
Post-Acute COVID-19 Syndrome Humans Feasibility Studies Pilot Projects Hand Strength Robotics Fatigue
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Feasibility Study of Constructing a Screening Tool for Adolescent Diabetes Detection Applying Machine Learning Methods.

Sensors (Basel, Switzerland) Aug 17, 2022
Prediabetes and diabetes are becoming alarmingly prevalent among adolescents over the past decade. However, an effective screening tool that can assess diabetes risks smoothly is still in its infancy. In order to contribute to such significant gaps, ...
Diabetes Mellitus Area Under Curve Feasibility Studies Adolescent Humans Nutrition Surveys Machine Learning
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Feasibility and safety of the da Vinci Xi surgical robot for transoral robotic surgery.

Journal of robotic surgery Aug 16, 2022
The collective experience supporting the safety and efficacy of transoral robotic surgery continues to grow. The surgical robot da Vinci Xi has been used successfully off-label for head and neck surgery, including transoral robotic surgery. We evalua...
Treatment Outcome Robotics Feasibility Studies Robotic Surgical Procedures Humans Retrospective Studies
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A Home-based Tele-rehabilitation System With Enhanced Therapist-patient Remote Interaction: A Feasibility Study.

IEEE journal of biomedical and health informatics Aug 11, 2022
As a promising alternative to hospital-based manual therapy, robot-assisted tele-rehabilitation therapy has shown significant benefits in reducing the therapist's workload and accelerating the patient's recovery process. However, existing telerobotic...
Movement Electromyography Feasibility Studies Robotics Telerehabilitation Humans
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