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Deep learning assessment of metastatic relapse risk from digitized breast cancer histological slides.
Nature communications
Jul 1, 2025
Accurate risk stratification is critical for guiding treatment decisions in early breast cancer. We present an artificial intelligence (AI)-based tool that analyzes digitized tumor slides to predict 5-year metastasis-free survival (MFS) in patients w...
A genotype-to-drug diffusion model for generation of tailored anti-cancer small molecules.
Nature communications
Jul 1, 2025
Despite advances in precision oncology, developing effective cancer therapeutics remains a significant challenge due to tumor heterogeneity and the limited availability of well-defined drug targets. Recent progress in generative artificial intelligen...
Enhanced role of the entorhinal cortex in adapting to increased working memory load.
Nature communications
Jul 1, 2025
In daily life, we frequently encounter varying demands on working memory (WM), yet how the brain adapts to high WM load remains unclear. To address this question, we recorded intracranial EEG from hippocampus, entorhinal cortex (EC), and lateral temp...
FPGA implementation of deep learning architecture for ankylosing spondylitis detection from MRI.
Scientific reports
Jul 1, 2025
Ankylosing Spondylitis (AS), commonly known as Bechterew's disease, is a complex, potentially disabling disease that develops slowly over time and progresses to radiographic sacroiliitis. The etiology of this disease is poorly understood, making it d...
Automated ejection fraction and risk stratification in cardiomyopathy patients with diverse LV geometry using 2D echocardiography.
Scientific reports
Jul 1, 2025
Cardiomyopathy often alters left ventricular geometry (LVG), impairing cardiac function. We developed a deep learning (DL) model to estimate left ventricular ejection fraction (LVEF) from echocardiographic images while accounting for LVG variability ...
Development and validation of an AI-enabled oral score using large-scale dental data.
Scientific reports
Jul 1, 2025
This research introduces Oral Score Basic (OS-B), a novel Artificial Intelligence (AI) derived methodology designed to provide a comprehensive, objective assessment of individual teeth and overall oral health, initially focused on dental conditions. ...
Automated sleep staging model for older adults based on CWT and deep learning.
Scientific reports
Jul 1, 2025
Sleep staging plays a crucial role in the diagnosis and treatment of sleep disorders. Traditional sleep staging requires manual classification by professional technicians based on the characteristic features of each sleep stage. This process is time-...
Prediction of axillary lymph node metastasis in triple negative breast cancer using MRI radiomics and clinical features.
Scientific reports
Jul 1, 2025
To develop and validate a machine learning-based prediction model to predict axillary lymph node (ALN) metastasis in triple negative breast cancer (TNBC) patients using magnetic resonance imaging (MRI) and clinical characteristics. This retrospective...
Predicting cisplatin response in cholangiocarcinoma patients using chromosome pattern and related gene expression.
Scientific reports
Jul 1, 2025
Cholangiocarcinoma (CCA) is a prevalent bile duct cancer with limited treatment options. Cisplatin-based chemotherapy is a common approach, but response rates vary. Recently, chromosome aberrations have emerged as predictors of chemotherapy response ...
Different prefrontal cortex activity patterns in bipolar and unipolar depression during verbal fluency tasks based on functional near infrared spectroscopy study.
Scientific reports
Jul 1, 2025
This study aimed to investigate the functionality of the prefrontal cortex in patients with unipolar depression (UD) and bipolar depression (BD) using functional near-infrared spectroscopy (fNIRS) during a verbal fluency task (VFT). Additionally, it ...
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