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Enrichment of extracellular vesicles using Mag-Net for the analysis of the plasma proteome.
Nature communications
Jul 1, 2025
Extracellular vesicles (EVs) in plasma are composed of exosomes, microvesicles, and apoptotic bodies. We report a plasma EV enrichment strategy using magnetic beads called Mag-Net. Proteomic interrogation of this plasma EV fraction enables the detect...
Decoding the diagnostic biomarkers of mitochondrial dysfunction related gene variants in pediatric T cell acute lymphoblastic leukemia.
Scientific reports
Jul 1, 2025
Mitochondrial dysfunction is crucial in the pathogenesis and drug resistance of pediatric T-cell acute lymphoblastic leukemia (T-ALL), a malignant hematological disorder with unrestrained proliferation of immature T-cells. Therefore, the primary obje...
Automatic pain classification in older patients with hip fracture based on multimodal information fusion.
Scientific reports
Jul 1, 2025
Given the limitations of unimodal pain recognition approaches, this study aimed to develop a multimodal pain recognition system for older patients with hip fractures using multimodal information fusion. The proposed system employs ResNet-50 for facia...
A novel feature extractor based on constrained cross network for detecting sleep state.
Scientific reports
Jul 1, 2025
With increasing awareness of healthy living and social pressure, more and more people have begun to pay attention to their sleep state. Most existing methods that utilize wrist-worn devices data for detection rely on heuristic algorithms or tradition...
Predicting car accident severity in Northwest Ethiopia: a machine learning approach leveraging driver, environmental, and road conditions.
Scientific reports
Jul 1, 2025
Road traffic accidents (RTAs) in Northwest Ethiopia, a region with a fatality rate of 32.2 per 100,000 residents, pose a critical public health challenge exacerbated by infrastructural deficits and environmental hazards. This study leverages machine ...
A superpixel based self-attention network for uterine fibroid segmentation in high intensity focused ultrasound guidance images.
Scientific reports
Jul 1, 2025
Ultrasound guidance images are widely used for high intensity focused ultrasound (HIFU) therapy; however, the speckles, acoustic shadows, and signal attenuation in ultrasound guidance images hinder the observation of the images by radiologists and ma...
Single pulse electrical stimulation of the medial thalamic surface induces narrower high gamma band activities in the sensorimotor cortex.
Scientific reports
Jul 1, 2025
The human thalamus projects nerve fibers to all cortical regions and propagates epileptic activity. However, opportunities to directly record thalamic and cortical neural activities simultaneously are extremely limited and their electrophysiological ...
A comprehensive study based on machine learning models for early identification Mycoplasma pneumoniae infection in segmental/lobar pneumonia.
Scientific reports
Jul 1, 2025
Segmental/lobar pneumonia in children following Mycoplasma pneumoniae (MP) infection has a significant threat to the children's health, so early recognition of MP infection is critical to reduce the severity and improve the prognosis of segmental/lob...
Auto-Segmentation via deep-learning approaches for the assessment of flap volume after reconstructive surgery or radiotherapy in head and neck cancer.
Scientific reports
Jul 1, 2025
Reconstructive flap surgery aims to restore the substance and function losses associated with tumor resection. Automatic flap segmentation could allow quantification of flap volume and correlations with functional outcomes after surgery or post-opera...
Predicting diabetic peripheral neuropathy through advanced plantar pressure analysis: a machine learning approach.
Scientific reports
Jul 1, 2025
Diabetic foot Ulceration (DFU) is a severe complication of diabetic foot syndrome, often leading to amputation. In patients with neuropathy, ulcer formation is facilitated by elevated plantar tissue stress under insensate feet. This study presents a ...
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