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Glioma

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Cooperative multi-task learning and interpretable image biomarkers for glioma grading and molecular subtyping.

Medical image analysis
Deep learning methods have been widely used for various glioma predictions. However, they are usually task-specific, segmentation-dependent and lack of interpretable biomarkers. How to accurately predict the glioma histological grade and molecular su...

MRI-derived radiomics and end-to-end deep learning models for predicting glioma ATRX status: a systematic review and meta-analysis of diagnostic test accuracy studies.

Clinical imaging
We aimed to systematically review and meta-analyze the predictive value of magnetic resonance imaging (MRI)-derived radiomics/end-to-end deep learning (DL) models in predicting glioma alpha thalassemia/mental retardation syndrome X-linked (ATRX) stat...

Deciphering the Role of SLFN12: A Novel Biomarker for Predicting Immunotherapy Outcomes in Glioma Patients Through Artificial Intelligence.

Journal of cellular and molecular medicine
Gliomas are the most prevalent form of primary brain tumours. Recently, targeting the PD-1 pathway with immunotherapies has shown promise as a novel glioma treatment. However, not all patients experience long-lasting benefits, underscoring the necess...

Clinical impact of an explainable machine learning with amino acid PET imaging: application to the diagnosis of aggressive glioma.

European journal of nuclear medicine and molecular imaging
PURPOSE: Radiomics-based machine learning (ML) models of amino acid positron emission tomography (PET) images have shown efficiency in glioma prediction tasks. However, their clinical impact on physician interpretation remains limited. This study inv...

Dual-path neural network extracts tumor microenvironment information from whole slide images to predict molecular typing and prognosis of Glioma.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Utilizing AI to mine tumor microenvironment information in whole slide images (WSIs) for glioma molecular subtype and prognosis prediction is significant for treatment. Existing weakly-supervised learning frameworks based on...

A hybrid explainable model based on advanced machine learning and deep learning models for classifying brain tumors using MRI images.

Scientific reports
Brain tumors present a significant global health challenge, and their early detection and accurate classification are crucial for effective treatment strategies. This study presents a novel approach combining a lightweight parallel depthwise separabl...

Deep learning-integrated MRI brain tumor analysis: feature extraction, segmentation, and Survival Prediction using Replicator and volumetric networks.

Scientific reports
The most prevalent form of malignant tumors that originate in the brain are known as gliomas. In order to diagnose, treat, and identify risk factors, it is crucial to have precise and resilient segmentation of the tumors, along with an estimation of ...

Weakly supervised deep learning-based classification for histopathology of gliomas: a single center experience.

Scientific reports
Multiple artificial intelligence systems have been created to facilitate accurate and prompt histopathological diagnosis of tumors using hematoxylin-eosin-stained slides. We aimed to investigate whether weakly supervised deep learning can aid in glio...

Multiparametric MRI along with machine learning predicts prognosis and treatment response in pediatric low-grade glioma.

Nature communications
Pediatric low-grade gliomas (pLGGs) exhibit heterogeneous prognoses and variable responses to treatment, leading to tumor progression and adverse outcomes in cases where complete resection is unachievable. Early prediction of treatment responsiveness...

Diagnostic Accuracy of Ambient Mass Spectrometry with Blood Plasma in a Murine Glioma Model Using Machine Learning.

World neurosurgery
OBJECTIVE: Malignant glioma progresses rapidly and shows poor prognosis, but clinically applicable blood plasma-based biochemical tumor markers remain lacking. This study aimed to develop a diagnostic system using probe electrospray ionization mass s...