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Gray Matter

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Multiple Holdouts With Stability: Improving the Generalizability of Machine Learning Analyses of Brain-Behavior Relationships.

Biological psychiatry
BACKGROUND: In 2009, the National Institute of Mental Health launched the Research Domain Criteria, an attempt to move beyond diagnostic categories and ground psychiatry within neurobiological constructs that combine different levels of measures (e.g...

Morphological Neuroimaging Biomarkers for Tinnitus: Evidence Obtained by Applying Machine Learning.

Neural plasticity
According to previous studies, many neuroanatomical alterations have been detected in patients with tinnitus. However, the results of these studies have been inconsistent. The objective of this study was to explore the cortical/subcortical morphologi...

SVM recursive feature elimination analyses of structural brain MRI predicts near-term relapses in patients with clinically isolated syndromes suggestive of multiple sclerosis.

NeuroImage. Clinical
Machine learning classification is an attractive approach to automatically differentiate patients from healthy subjects, and to predict future disease outcomes. A clinically isolated syndrome (CIS) is often the first presentation of multiple sclerosi...

Simultaneous Tissue Classification and Lateral Ventricle Segmentation via a 2D U-net Driven by a 3D Fully Convolutional Neural Network.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
In this paper, we proposed and validated a novel and fully automatic pipeline for simultaneous tissue classification and lateral ventricle segmentation via a 2D U-net. The 2D U-net was driven by a 3D fully convolutional neural network (FCN). Multiple...

Prediction of Multiple Sclerosis Patient Disability from Structural Connectivity using Convolutional Neural Networks.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Prediction of disability progression in multiple sclerosis patients is a critical component of their management. In particular, one challenge is to identify and characterize a patient profile who may benefit of efficient treatments. However, it is no...

Unsupervised machine learning using an imaging mass spectrometry dataset automatically reassembles grey and white matter.

Scientific reports
Current histological and anatomical analysis techniques, including fluorescence in situ hybridisation, immunohistochemistry, immunofluorescence, immunoelectron microscopy and fluorescent fusion protein, have revealed great distribution diversity of m...

Integrating machining learning and multimodal neuroimaging to detect schizophrenia at the level of the individual.

Human brain mapping
Schizophrenia is a severe psychiatric disorder associated with both structural and functional brain abnormalities. In the past few years, there has been growing interest in the application of machine learning techniques to neuroimaging data for the d...

Disentangling brain functional network remodeling in corticobasal syndrome - A multimodal MRI study.

NeuroImage. Clinical
OBJECTIVE: The clinical diagnosis of corticobasal syndrome (CBS) represents a challenge for physicians and reliable diagnostic imaging biomarkers would support the diagnostic work-up. We aimed to investigate the neural signatures of CBS using multimo...

Identification of patients with and without minimal hepatic encephalopathy based on gray matter volumetry using a support vector machine learning algorithm.

Scientific reports
Minimal hepatic encephalopathy (MHE) is characterized by diffuse abnormalities in cerebral structure, such as reduced cortical thickness and altered brain parenchymal volume. This study tested the potential of gray matter (GM) volumetry to differenti...