Immune checkpoint blockade (ICB) is the standard of care for recurrent/metastatic head and neck squamous cell carcinoma (HNSCC), yet efficacy remains low. The combined positive score (CPS) for PD-L1 is the only biomarker approved to predict response ...
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Feb 18, 2025
INTRODUCTION: This article explores the potential role of artificial intelligence (AI) in enhancing the early detection and diagnosis of head and neck squamous cell carcinoma (HNSCC).
. Deep learning (DL)-based automated contouring and treatment planning has been proven to improve the efficiency and accuracy of radiotherapy. However, conventional radiotherapy treatment planning process has the automated contouring and treatment pl...
Cancer imaging : the official publication of the International Cancer Imaging Society
Feb 16, 2025
BACKGROUND: Immunotherapy has revolutionized the treatment landscape for head and neck squamous cell carcinoma (HNSCC) and PD-L1 combined positivity score (CPS) scoring is recommended as a biomarker for immunotherapy. Therefore, this study aimed to d...
AIM: This review aims to evaluate the role of interventional radiotherapy (IRT - brachytherapy) in the clinical management of head and neck (H&N) cancers, focusing on recent technological advancements and their impact on clinical outcomes.
BACKGROUND: Given the recent increased emphasis on multimodal neural networks to solve complex modeling tasks, the problem of outcome prediction for a course of treatment can be framed as fundamentally multimodal in nature. A patient's response to tr...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Feb 8, 2025
PURPOSE: This study investigated the effect of multiple magnetic resonance (MR) sequences on the quality of deep-learning-based synthetic computed tomography (sCT) generation in the head and neck region.
BACKGROUND: Immunotherapy has introduced new breakthroughs in improving the survival of head and neck squamous cell carcinoma (HNSCC) patients, yet drug resistance remains a critical challenge. Developing personalized treatment strategies based on th...
Biomedical physics & engineering express
Feb 6, 2025
. Although radiotherapy techniques are a primary treatment for head and neck cancer (HNC), they are still associated with substantial toxicity and side effects. Machine learning (ML) based radiomics models for predicting toxicity mostly rely on featu...
IEEE transactions on neural networks and learning systems
Feb 6, 2025
Next-generation sequencing (NGS) genomic data offer valuable high-throughput genomic information for computational applications in medicine. Using genomic data to identify disease-associated genes to estimate cancer mortality risk remains challenging...
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