AIMC Topic: Homeostasis
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Effects of sevoflurane versus propofol on cerebral autoregulation during anaesthesia for robot-assisted laparoscopic prostatectomy.
Anaesthesia and intensive care
May 15, 2022
Robot-assisted laparoscopic prostatectomy requires a pneumoperitoneum combined with steep Trendelenburg positioning, and these conditions can be associated with impairment of cerebral autoregulation. The objective of this study was to determine if ch...
Percolation in networks with local homeostatic plasticity.
Nature communications
Jan 10, 2022
Percolation is a process that impairs network connectedness by deactivating links or nodes. This process features a phase transition that resembles paradigmatic critical transitions in epidemic spreading, biological networks, traffic and transportati...
The rise of intelligent matter.
Nature
Jun 16, 2021
Artificial intelligence (AI) is accelerating the development of unconventional computing paradigms inspired by the abilities and energy efficiency of the brain. The human brain excels especially in computationally intensive cognitive tasks, such as p...
A computational framework for optimal control of a self-adjustive neural system with activity-dependent and homeostatic plasticity.
NeuroImage
Jan 30, 2021
The control of the brain system has received increasing attention in the domain of brain science. Most brain control studies have been conducted to explore the brain network's graph-theoretic properties or to produce the desired state based on neural...
The proteome landscape of the kingdoms of life.
Nature
Jun 17, 2020
Proteins carry out the vast majority of functions in all biological domains, but for technological reasons their large-scale investigation has lagged behind the study of genomes. Since the first essentially complete eukaryotic proteome was reported, ...
Machine Learning to Support Hemodynamic Intervention in the Neonatal Intensive Care Unit.
Clinics in perinatology
May 20, 2020
Hemodynamic support in neonatal intensive care is directed at maintaining cardiovascular wellbeing. At present, monitoring of vital signs plays an essential role in augmenting care in a reactive manner. By applying machine learning techniques, a mode...
The NAD-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications.
Mechanisms of ageing and development
Dec 5, 2019
Nicotinamide adenine dinucleotide (NAD) is an important natural molecule involved in fundamental biological processes, including the TCA cycle, OXPHOS, β-oxidation, and is a co-factor for proteins promoting healthy longevity. NAD depletion is associa...
Constructing multilayered neural networks with sparse, data-driven connectivity using biologically-inspired, complementary, homeostatic mechanisms.
Neural networks : the official journal of the International Neural Network Society
Oct 5, 2019
The immense complexity of the brain requires that it be built and controlled by intrinsic, self-regulating mechanisms. One such mechanism, the formation of new connections via synaptogenesis, plays a central role in neuronal connectivity and, ultimat...
Stable memory with unstable synapses.
Nature communications
Sep 30, 2019
What is the physiological basis of long-term memory? The prevailing view in Neuroscience attributes changes in synaptic efficacy to memory acquisition, implying that stable memories correspond to stable connectivity patterns. However, an increasing b...
More Than Just a Removal Service: Scavenger Receptors in Leukocyte Trafficking.
Frontiers in immunology
Dec 12, 2018
Scavenger receptors are a highly diverse superfamily of proteins which are grouped by their inherent ability to bind and internalize a wide array of structurally diverse ligands which can be either endogenous or exogenous in nature. Consequently, sca...
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