AIMC Topic: Humans

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Identification and validation of oxidative stress-related genes in biliary atresia.

Pediatric surgery international
PURPOSE: Increasing evidence has indicated a role of oxidative stress in the pathogenesis of biliary atresia (BA). This study aimed to identify key oxidative stress-related biomarkers in BA and explore their therapeutic potential.

Multimodal prediction of psychotic-like experiences using elastic net modeling: external validation in a clinical sample.

Psychological medicine
BACKGROUND: Psychotic-like experiences (PLEs) are considered a subclinical component of psychosis continuum. Studies indicate that PLEs arise from multimodal factors, yet research comprehensively examining these factors together remains scarce. Using...

Mapping respiratory health digital interventions in South and Southeast Asia: a scoping review.

Journal of global health
BACKGROUND: The growing burden of respiratory disease, particularly in Asia, where mortality is higher and awareness and policy engagement lag, could be mitigated through rapidly advancing digital health tools that offer opportunities for improved ma...

WHO global research priorities for traditional, complementary, and integrative (TCI) medicine: an international consensus and comparisons with LLMs.

Journal of global health
BACKGROUND: Traditional, complementary, and integrative (TCI) medicine is an essential component of health systems worldwide, especially in low- and middle-income countries. Despite its widespread use, existing research on the safety, efficacy, and i...

TF-crossnet: a cross-modal attention fusion network for cardiovascular disease classification using pcg and ecg signals.

Biomedical physics & engineering express
Electrocardiogram (ECG) and phonocardiogram (PCG) have emerged as crucial non-invasive and portable diagnostic modalities for early cardiovascular disease (CVD) screening. Despite the individual merits of these signal modalities in CVD detection, sig...

AI-driven software for automated quantification of skeletal metastases and treatment response evaluation using whole-body diffusion-weighted MRI (WB-DWI) in advanced prostate cancer.

Physics in medicine and biology
. Quantitative assessment of treatment response in advanced prostate cancer (APC) with bone metastases remains an unmet clinical need. Whole-body diffusion-weighted MRI (WB-DWI) provides two response biomarkers: total diffusion volume (TDV) and globa...

Impact of patient-specific deep learning lung organs-at-risk segmentation on accumulated dose in online adaptive 0.35 T MR-guided radiotherapy.

Physics in medicine and biology
Online adaptation in magnetic resonance imaging-guided radiotherapy (MRgRT) for lung cancer is hindered by time-consuming organs-at-risk (OARs) recontouring on daily MR images (dMRIs) and inter-/intra-observer variability. Deep learning auto-segmenta...

Applied machine learning for nociceptive pain detection using EEG spectral features.

Biomedical physics & engineering express
. This study explores a more reliable method for measuring nociceptive pain induced by laser stimuli from electroencephalography (EEG) signals, addressing the limitations of fixed pain scales by incorporating inter-individual variability in subjectiv...

Deepfake defense: Combining spatial and temporal cues with CNN-BiLSTM-transformer architecture.

PloS one
The proliferation of deepfakes is a major threat to the believability of online media and the stability of public discourse. These hyper-realistic fake videos, nearly indistinguishable from genuine content, can be misused to spread disinformation, co...

Enhancing sarcasm detection on social media: A comprehensive study using LLMs and BERT with multi-headed attention on SARC.

PloS one
Sarcasm detection in natural language processing (NLP) remains a complex challenge, especially in social media, where contextual clues are often subtle. This study addresses this challenge by leveraging transformer-based models, including BERT, GPT-3...