AIMC Topic: Humans

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The effect of thalidomide on the invasive ability of gastric cancer cells by regulating miR-524-5p/FSTL1.

Cellular and molecular biology (Noisy-le-Grand, France)
This study aimed to investigate the effect of thalidomide (Thal) regulating microRNA (miR)-524-5p/follistatin-like protein 1 (FSTL1) on the invasion ability of gastric cancer cells. For this purpose, real-time fluorescent quantitative PCR (RT-qPCR) w...

Bioactive Molecules from the Innate Immunity of Ascidians and Innovative Methods of Drug Discovery: A Computational Approach Based on Artificial Intelligence.

Marine drugs
The study of bioactive molecules of marine origin has created an important bridge between biological knowledge and its applications in biotechnology and biomedicine. Current studies in different research fields, such as biomedicine, aim to discover m...

Quantitative Rapid Magnetic Immunoassay for Sensitive Toxin Detection in Food: Non-Covalent Functionalization of Nanolabels vs. Covalent Immobilization.

Toxins
In this study, we present a novel and ultrasensitive magnetic lateral flow immunoassay (LFIA) tailored for the precise detection of zearalenone, a mycotoxin with significant implications for human and animal health. A versatile and straightforward me...

Accuracy Comparison between Robot-Assisted Dental Implant Placement and Static/Dynamic Computer-Assisted Implant Surgery: A Systematic Review and Meta-Analysis of In Vitro Studies.

Medicina (Kaunas, Lithuania)
: The present systematic review and meta-analysis undertake a comparison of studies that examine the accuracy of robot-assisted dental implant placement in relation to static computer-assisted implant surgery (SCAIS), dynamic computer-assisted implan...

Humoral Immune Responses after an Omicron-Adapted Booster BNT162b2 Vaccination in Patients with Lymphoid Malignancies.

Viruses
To accommodate waning COVID-19 vaccine immunity to emerging SARS-CoV-2 variants, variant-adapted mRNA vaccines have been introduced. Here, we examine serological responses to the BA.1 and BA.4-5 Omicron variant-adapted BNT162b2 COVID-19 vaccines in p...

Deep Learning Model for Classifying and Evaluating Soybean Leaf Disease Damage.

International journal of molecular sciences
Soybean ( (L.) Merr.) is a major source of oil and protein for human food and animal feed; however, soybean crops face diverse factors causing damage, including pathogen infections, environmental shifts, poor fertilization, and incorrect pesticide us...

MRI/RNA-Seq-Based Radiogenomics and Artificial Intelligence for More Accurate Staging of Muscle-Invasive Bladder Cancer.

International journal of molecular sciences
Accurate staging of bladder cancer assists in identifying optimal treatment (e.g., transurethral resection vs. radical cystectomy vs. bladder preservation). However, currently, about one-third of patients are over-staged and one-third are under-stage...

Distinctive approach in brain tumor detection and feature extraction using biologically inspired DWT method and SVM.

Scientific reports
Brain tumors result from uncontrolled cell growth, potentially leading to fatal consequences if left untreated. While significant efforts have been made with some promising results, the segmentation and classification of brain tumors remain challengi...

COVID-19 infection segmentation using hybrid deep learning and image processing techniques.

Scientific reports
The coronavirus disease 2019 (COVID-19) epidemic has become a worldwide problem that continues to affect people's lives daily, and the early diagnosis of COVID-19 has a critical importance on the treatment of infected patients for medical and healthc...

Holistic Human-Serving Digitization of Health Care Needs Integrated Automated System-Level Assessment Tools.

Journal of medical Internet research
Digital health tools, platforms, and artificial intelligence- or machine learning-based clinical decision support systems are increasingly part of health delivery approaches, with an ever-greater degree of system interaction. Critical to the successf...