Medical oncology (Northwood, London, England)
Dec 24, 2025
Non-small cell lung cancer (NSCLC) presents significant therapeutic challenges due to resistance and immune evasion. Dihydroartemisinin (DHA), a derivative of artemisinin, exhibits broad anti-tumor activity, but its molecular targets and mechanisms i...
World journal of microbiology & biotechnology
Dec 24, 2025
Bacterial detection and identification is paramount as it plays a key role in safeguarding human health, food safety and security. Over the past decade, biosensors have emerged as a powerful tool for bacterial detection due to their ability to provid...
Journal of computer-aided molecular design
Dec 24, 2025
In recent decades, the rapid pace of digital transformation marks a transformative era for the healthcare and pharmaceutical industries. The incorporation of innovative technology, specifically Artificial Intelligence (AI) and its derivatives, has dr...
Current treatment options in oncology
Dec 24, 2025
Improved survival in pediatric oncology has highlighted the growing burden of cancer treatment-related cardiotoxicity among survivors of childhood cancers. While the cardiotoxicity of anthracyclines and chest radiation are well documented as major co...
Biomedical physics & engineering express
Dec 24, 2025
Intelligent computer-aided diagnosis techniques enable inspection of invisible electrocardiogram (ECG) pathological changes for early detection of latent heart diseases. This study concentrates on latent pathological changes within non-episodic ECG d...
BACKGROUND: The burden of cardiovascular events in Africa is projected to rise significantly in the coming decade, placing additional strain on already overburdened healthcare systems. Mobile health (mHealth) technologies present a promising approach...
Rome IV disorders of gut-brain interaction (DGBI) subtypes are known to be unstable and demonstrate high rates of non-treatment response, likely indicating patient heterogeneity. Cluster analysis, a type of unsupervised machine learning, can identify...
Journal of chemical information and modeling
Dec 23, 2025
Accurate protein subcellular localization (PSL) is essential for proteins to perform their biological functions, whereas protein mis-localization can disrupt cellular processes and contribute to various diseases, particularly cancer. Although spatial...
Journal of chemical information and modeling
Dec 23, 2025
Target-specific scoring functions offer a promising route to improve structure-based virtual screening beyond generic, bias-prone scoring schemes. Here, we introduce AttentionScore, a deep learning-based scoring function for METTL3 that integrates li...
Journal of chemical information and modeling
Dec 23, 2025
Antimicrobial peptides have emerged as a potential alternative to traditional small-molecule antimicrobials. They possess broad-spectrum efficacy and increasingly confront the challenges of bacterial resistance, especially the adaptive resistance of ...
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