AIMC Topic: Humans

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Fast operating room scattered radiation calculation in x-ray guided interventions by using deep learning.

Journal of radiological protection : official journal of the Society for Radiological Protection
Protecting medical personnel from the harmful effects of scattered ionising radiation during x-ray-guided procedures is a critical concern. Due to the complex and invisible nature of x-rays, monitoring radiation exposure has been challenging. Existin...

Twelve Practical Tips for Integrating AI Into Medical Education: Tutorial to Support Educators Across Teaching, Research, Administration, and Ethical Domains.

JMIR medical education
Artificial intelligence (AI) is rapidly reshaping medical education, offering new opportunities to personalize learning, enhance research, and streamline administration. The aim of this study is to provide 12 practical, evidence-informed tips by draw...

Scout-Dose-TCM: direct and prospective scout-based estimation of personalized organ and effective doses from tube current modulated CT exams.

Physics in medicine and biology
This study proposes Scout-Dose-TCM for direct, prospective estimation of organ-level and effective doses under tube current modulation (TCM) and compares its performance with two established methods.Contrast-enhanced chest-abdomen-pelvis CT exams fro...

Knowledge, attitudes and practices toward artificial intelligence among pediatricians in India: A cross-sectional web-based nationwide survey.

PloS one
BACKGROUND: Artificial intelligence (AI) is rapidly advancing in healthcare and has the potential to transform patient care. This study aimed to assess the knowledge, attitudes, and practices (KAP) regarding AI among pediatricians in India.

R2GDN: RepGhost based residual dense network for image super-resolution.

PloS one
This study introduces a novel lightweight image super-resolution reconstruction network aimed at mitigating the challenges associated with computational complexity and memory consumption in existing super-resolution reconstruction networks. The propo...

Machine learning-guided identification and simulation-based validation of potent JAK3 inhibitors for cancer therapy.

PloS one
Janus kinase 3 (JAK3) is a hematopoietic-specific kinase implicated in cytokine signaling and immune dysregulation and has recently been associated with cancer progression. However, selective and potent JAK3 inhibitors remain underdeveloped. In this ...

Mechanisms of Adeno-Associated Virus Serotype 9 Vector Characterization and Quality Control through Solid-State Nanopores.

ACS nano
Adeno-associated virus (AAV) vectors are excellent gene-delivery carriers in gene therapy; however, improperly packaged capsids produced during manufacturing can reduce potency and raise safety concerns. We introduce a machine-learning-assisted, low-...

Enhancing clinicians' trust in large language models via transparent source attribution: A randomized controlled evaluation in uro-oncology.

European journal of cancer (Oxford, England : 1990)
INTRODUCTION: Large language models (LLMs) are utilized to answer queries in urology and oncology, yet the performance is limited due to outdated data and missing source transparency, which undermines clinical reliability and therefore adoption. MATE...

Descriptor-First Approach for ADMET Prediction in the PolarisHub Antiviral Challenge.

Journal of chemical information and modeling
The prediction of absorption, distribution, metabolism, excretion, and toxicity (ADMET) properties remains a central bottleneck in small-molecule discovery. We present the third-place solution from the PolarisHub Antiviral Competition, covering five ...

Deconvoluting Biophysical Factors that Influence Long-Term Aggregation Rates of High-Concentration Monoclonal Antibody Formulations.

Molecular pharmaceutics
Efficient determination of developable protein drug candidates and stable solution conditions is a key challenge in industrial drug development. Protein aggregation is difficult to predict and can lead to challenges in manufacturing, storage, and pat...