AIMC Topic: Humans
Showing 66301 to 66310 of 95995 articles
Extracting chemical-protein interactions from literature using sentence structure analysis and feature engineering.
Database : the journal of biological databases and curation
Jan 1, 2019
Information about the interactions between chemical compounds and proteins is indispensable for understanding the regulation of biological processes and the development of therapeutic drugs. Manually extracting such information from biomedical litera...
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Combining relation extraction with function detection for BEL statement extraction.
Database : the journal of biological databases and curation
Jan 1, 2019
The BioCreative-V community proposed a challenging task of automatic extraction of causal relation network in Biological Expression Language (BEL) from the biomedical literature. Previous studies on this task largely used models induced from other re...
State-of-the-art review on deep learning in medical imaging.
Frontiers in bioscience (Landmark edition)
Jan 1, 2019
Deep learning (DL) is affecting each and every sphere of public and private lives and becoming a tool for daily use. The power of DL lies in the fact that it tries to imitate the activities of neurons in the neocortex of human brain where the thought...
Application of machine learning in rheumatic disease research.
The Korean journal of internal medicine
Dec 31, 2018
Over the past decade, there has been a paradigm shift in how clinical data are collected, processed and utilized. Machine learning and artificial intelligence, fueled by breakthroughs in high-performance computing, data availability and algorithmic i...
Quantitation of serum 25(OH)D2 and 25(OH)D3 concentrations by liquid chromatography tandem mass spectrometry in patients with diabetes mellitus.
Journal of food and drug analysis
Dec 31, 2018
Vitamin D has been considered to regulate calcium and phosphorus homeostasis and to preserve skeletal integrity. Serum 25-hydroxyvitamin D (25(OH)D) is the best indicator of vitamin D levels. The association of serum 25(OH)D deficiency with increased...
Design and synthesis of new phthalazine-based derivatives as potential EGFR inhibitors for the treatment of hepatocellular carcinoma.
Bioorganic chemistry
Dec 31, 2018
Searching for new leads in the battle of cancer will never ends, we herein disclose the design and synthesis of new phthalazine derivatives and their in vitro and in vivo testing for their antiproliferative activity. Phthalazine was selected as a pri...
Quantitative analysis of manual annotation of clinical text samples.
International journal of medical informatics
Dec 31, 2018
BACKGROUND: Semantic interoperability of eHealth services within and across countries has been the main topic in several research projects. It is a key consideration for the European Commission to overcome the complexity of making different health in...
Deep Learning for Musculoskeletal Force Prediction.
Annals of biomedical engineering
Dec 31, 2018
Musculoskeletal models permit the determination of internal forces acting during dynamic movement, which is clinically useful, but traditional methods may suffer from slowness and a need for extensive input data. Recently, there has been interest in ...
Intensity-modulated radiation therapy of anal squamous cell carcinoma: Relationship between delineation quality and regional recurrence.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Dec 31, 2018
BACKGROUND AND PURPOSE: Intensity-modulated radiation therapy (IMRT) is currently indicated to treat anal squamous cell carcinoma (ASCC). Conformal dose delivery and steep dose gradients may cause marginal misses. We analyzed patterns of locoregional...
MITK Phenotyping: An open-source toolchain for image-based personalized medicine with radiomics.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Dec 31, 2018
Radiomics - The extraction of quantitative features from radiologic images - shows increasing potential in contributing to modern personalized medicine approaches. MITK Phenotyping is an openly distributed radiomics framework implementing an exhausti...
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