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An Uncontrolled Manifold Analysis of Arm Joint Variability in Virtual Planar Position and Orientation Telemanipulation.

IEEE transactions on bio-medical engineering
OBJECTIVE: In teleoperated robot-assisted tasks, the user interacts with manipulators to finely control remote tools. Manipulation of robotic devices, characterized by specific kinematic and dynamic proprieties, is a complex task for the human sensor...
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Nonlinear analysis and synthesis of video images using deep dynamic bottleneck neural networks for face recognition.

Neural networks : the official journal of the International Neural Network Society
Nonlinear components extracted from deep structures of bottleneck neural networks exhibit a great ability to express input space in a low-dimensional manifold. Sharing and combining the components boost the capability of the neural networks to synthe...

Intelligent Network DisRuption Analysis (INDRA): A targeted strategy for efficient interruption of hepatitis C transmissions.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
Hepatitis C virus (HCV) infection is a global public health problem. The implementation of public health interventions (PHI) to control HCV infection could effectively interrupt HCV transmission. PHI targeting high-risk populations, e.g., people who ...

Pedicle Screw Revision in Robot-Guided, Navigated, and Freehand Thoracolumbar Instrumentation: A Systematic Review and Meta-Analysis.

World neurosurgery
OBJECTIVE: Various computer-based guidance systems have been devised to reduce costly screw-related complications, yet their clinical effectiveness has never been comparatively assessed in a meta-analysis. We aimed to evaluate the incidence of clinic...

Redefining the Protein Kinase Conformational Space with Machine Learning.

Cell chemical biology
Protein kinases are dynamic, adopting different conformational states that are critical for their catalytic activity. We assess a range of structural features derived from the conserved αC helix and DFG motif to define the conformational space of the...

Host Cell Prediction of Exosomes Using Morphological Features on Solid Surfaces Analyzed by Machine Learning.

The journal of physical chemistry. B
Exosomes are extracellular nanovesicles released from any cells and found in any body fluid. Because exosomes exhibit information of their host cells (secreting cells), their analysis is expected to be a powerful tool for early diagnosis of cancers. ...

Profiling Lung Cancer Patients Using Electronic Health Records.

Journal of medical systems
If Electronic Health Records contain a large amount of information about the patient's condition and response to treatment, which can potentially revolutionize the clinical practice, such information is seldom considered due to the complexity of its ...

Genome-wide prediction of cis-regulatory regions using supervised deep learning methods.

BMC bioinformatics
BACKGROUND: In the human genome, 98% of DNA sequences are non-protein-coding regions that were previously disregarded as junk DNA. In fact, non-coding regions host a variety of cis-regulatory regions which precisely control the expression of genes. T...