The exploration of anticancer drugs has aimed at more effective, adaptable, and less harmful treatments, with natural products pivotal in cancer research. In addition to experimental techniques for identifying anticancer drug candidates, computationa...
BACKGROUND: Computed tomography (CT) has been widely used as an effective tool for liver imaging due to its high spatial resolution, and ability to differentiate tissue densities, which contributing to comprehensive image analysis. Recent advancement...
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Jun 3, 2025
BACKGROUND: Delays in management and misdiagnosis are common in patients with spinal dural arteriovenous fistula (sdAVF). In this study we review the incidence of delays, where they occur in the diagnostic process, who is responsible and what are the...
Development of acquired therapeutic resistance limits the efficacy of cancer treatments and accounts for therapeutic failure in most patients. How resistance arises, varies across cancer types and differs depending on therapeutic modalities is incomp...
Lung cancer is the leading cause of cancer mortality among people with HIV (PWH), with increased incidence and poor outcomes. This study explored whether the tumor microenvironment (TME) of HIV-associated non-small cell lung cancer (NSCLC) limits tum...
ACS biomaterials science & engineering
Jun 3, 2025
Microalgae robots are an emerging biohybrid microrobot that combines the biological properties of microalgae with microrobot technology and shows a wide range of applications in the medical field. In recent years, it has been found that microalgae ar...
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Jun 3, 2025
Myocardial fibrosis, a hallmark of heart failure (HF), contributes to disease progression and mortality by impairing cardiac function. Despite the identification of potential anti-fibrotic molecules, there is a lack of effective pharmacological inter...
Biohybrid microrobots, based on swimming microalgae, offer outstanding self-propulsion and functionalization capabilities, making them promising platforms for cargo loading and delivery. However, current technologies predominantly focus on in vitro n...
The safety of inorganic nanoparticles (NPs) remains a critical challenge for their clinical translation. To address this, we developed a machine learning (ML) framework that predicts NP toxicity both and , leveraging physicochemical properties and e...
ConspectusThe escalating threat of antimicrobial resistance (AMR) poses a significant global health crisis, potentially surpassing cancer as a leading cause of death by 2050. Traditional antibiotic discovery methods have not kept pace with the rapidl...
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