AIMC Topic: Intestines

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Mechanistic Insights into the Effects of Liquid Crystalline Monomers on Intestinal Stem Cell Differentiation Imbalance by Integrating Machine Learning and Adverse Outcome Pathway Framework Based on Organoids.

Environmental science & technology
The global annual output of liquid crystal monomers (LCMs) continues to increase, yet associated environmental and health risks remain poorly characterized. Assessing the toxic effects of the LCM mixture and individual components is critical for risk...

Intestinal bacteria translocation promotes β-cell dysfunction in DIO mice.

Scientific reports
Awareness of the intestinal microflora involved in insulin resistance and type 2 diabetes (T2DM) has now become more evident. However, direct mechanical insight is required to illustrate the contribution of intestinal microflora in the disease progre...

Deconvolution of cell types and states in spatial multiomics utilizing TACIT.

Nature communications
Identifying cell types and states remains a time-consuming, error-prone challenge for spatial biology. While deep learning increasingly plays a role, it is difficult to generalize due to variability at the level of cells, neighborhoods, and niches in...

Multi-dimensional consistency learning between 2D Swin U-Net and 3D U-Net for intestine segmentation from CT volume.

International journal of computer assisted radiology and surgery
PURPOSE: The paper introduces a novel two-step network based on semi-supervised learning for intestine segmentation from CT volumes. The intestine folds in the abdomen with complex spatial structures and contact with neighboring organs that bring dif...

Deliod a lightweight detection model for intestinal organoids based on deep learning.

Scientific reports
Intestinal organoids are indispensable tools for exploring intestinal disorders. Deep learning methodologies are often employed in morphological analysis to evaluate the condition of these organoids. Nonetheless, prevailing analytical techniques face...

Physalis Calyx seu Fructus relieves chicken intestinal damage to heat via improving the antioxidant ability.

Frontiers in immunology
Heat-stress-induced oxidative and inflammatory responses were important factors contributing to chicken intestinal damage. The purpose of this study was based on the antioxidant and anti-inflammatory activities of Physalis Calyx seu Fructus (Jin Deng...

Accelerated T2-weighted MRI of the Bowel at 3T Using a Single-shot Technique with Deep Learning-based Image Reconstruction: Impact on Image Quality and Disease Detection.

Academic radiology
RATIONALE AND OBJECTIVE: A single-shot T2-weighted deep-learning-based image reconstruction (DL-HASTE) has been recently developed allowing for shorter acquisition time than conventional half-Fourier acquisition single-shot turbo-spin echo (HASTE). T...

Role of artificial intelligence in Crohn's disease intestinal strictures and fibrosis.

Journal of digestive diseases
Crohn's disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract. Intestinal fibrosis or stricture is one of the most prevalent complications in CD with a high recurrence rate. Manual examination of intestinal fibrosis or strictu...

OrgaSegment: deep-learning based organoid segmentation to quantify CFTR dependent fluid secretion.

Communications biology
Epithelial ion and fluid transport studies in patient-derived organoids (PDOs) are increasingly being used for preclinical studies, drug development and precision medicine applications. Epithelial fluid transport properties in PDOs can be measured th...