AIMC Topic: Kidney Neoplasms

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Artificial intelligence algorithms enhance urine cytology reporting confidence in postoperative follow-up for upper urinary tract urothelial carcinoma.

International urology and nephrology
PURPOSE: In Taiwan, the incidence of urothelial carcinoma of the upper urinary tract (UTUC) is high and intravesical recurrence is approximately 22%-47%. Thus, postoperative cystoscopy and urine cytology follow-up, which require experienced cytologis...

Construction of a Wilms tumor risk model based on machine learning and identification of cuproptosis-related clusters.

BMC medical informatics and decision making
BACKGROUND: Cuproptosis, a recently identified type of programmed cell death triggered by copper, has mechanisms in Wilms tumor (WT) that are not yet fully understood. This research focuses on examining the link between WT and Cuproptosis-related gen...

Three-dimensional deep learning model complements existing models for preoperative disease-free survival prediction in localized clear cell renal cell carcinoma: a multicenter retrospective cohort study.

International journal of surgery (London, England)
BACKGROUND: Current prognostic models have limited predictive abilities for the growing number of localized (stage I-III) ccRCCs. It is, therefore, crucial to explore novel preoperative recurrence prediction models to accurately stratify patients and...

Aggressiveness classification of clear cell renal cell carcinoma using registration-independent radiology-pathology correlation learning.

Medical physics
BACKGROUND: Renal cell carcinoma (RCC) is a common cancer that varies in clinical behavior. Clear cell RCC (ccRCC) is the most common RCC subtype, with both aggressive and indolent manifestations. Indolent ccRCC is often low-grade without necrosis an...

Triple and quadruple optimization for feature selection in cancer biomarker discovery.

Journal of biomedical informatics
The proliferation of omics data has advanced cancer biomarker discovery but often falls short in external validation, mainly due to a narrow focus on prediction accuracy that neglects clinical utility and validation feasibility. We introduce three- a...

A Robust Deep Learning Method with Uncertainty Estimation for the Pathological Classification of Renal Cell Carcinoma Based on CT Images.

Journal of imaging informatics in medicine
This study developed and validated a deep learning-based diagnostic model with uncertainty estimation to aid radiologists in the preoperative differentiation of pathological subtypes of renal cell carcinoma (RCC) based on computed tomography (CT) ima...

Machine Learning-Enabled Fuhrman Grade in Clear-cell Renal Carcinoma Prediction Using Two-dimensional Ultrasound Images.

Ultrasound in medicine & biology
OBJECTIVE: Accurate assessment of Fuhrman grade is crucial for optimal clinical management and personalized treatment strategies in patients with clear cell renal cell carcinoma (CCRCC). In this study, we developed a predictive model using ultrasound...

RCC-Supporter: supporting renal cell carcinoma treatment decision-making using machine learning.

BMC medical informatics and decision making
BACKGROUND: The population diagnosed with renal cell carcinoma, especially in Asia, represents 36.6% of global cases, with the incidence rate of renal cell carcinoma in Korea steadily increasing annually. However, treatment options for renal cell car...

Renal Cell Carcinoma Discrimination through Attenuated Total Reflection Fourier Transform Infrared Spectroscopy of Dried Human Urine and Machine Learning Techniques.

International journal of molecular sciences
Renal cell carcinoma (RCC) is the sixth most common cancer in men and is often asymptomatic, leading to incidental detection in advanced disease stages that are associated with aggressive histology and poorer outcomes. Various cancer biomarkers are f...