AIMC Topic: Leukemia, Myeloid, Acute

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How to predict relapse in leukemia using time series data: A comparative in silico study.

PloS one
Risk stratification and treatment decisions for leukemia patients are regularly based on clinical markers determined at diagnosis, while measurements on system dynamics are often neglected. However, there is increasing evidence that linking quantitat...

Job characteristics of a Malaysian bank's anti-money laundering system and its employees' job satisfaction.

F1000Research
Banks and financial institutions are vulnerable to money laundering (ML) as a result of crime proceeds infiltrating banks in the form of significant cash deposits. Improved financial crime compliance processes and systems enable anti-ML (AML) analys...

Deep learning detects acute myeloid leukemia and predicts NPM1 mutation status from bone marrow smears.

Leukemia
The evaluation of bone marrow morphology by experienced hematopathologists is essential in the diagnosis of acute myeloid leukemia (AML); however, it suffers from a lack of standardization and inter-observer variability. Deep learning (DL) can proces...

Identification of biomarkers for acute leukemia via machine learning-based stemness index.

Gene
Traditional methods to understand leukemia stem cell (LSC)'s biological characteristics include constructing LSC-like cells and mouse models by transgenic or knock-in methods. However, there are some potential pitfalls in using this method, such as r...

Unsupervised machine learning reveals key immune cell subsets in COVID-19, rhinovirus infection, and cancer therapy.

eLife
For an emerging disease like COVID-19, systems immunology tools may quickly identify and quantitatively characterize cells associated with disease progression or clinical response. With repeated sampling, immune monitoring creates a real-time portrai...

Survival prognostic factors in patients with acute myeloid leukemia using machine learning techniques.

PloS one
This paper identifies prognosis factors for survival in patients with acute myeloid leukemia (AML) using machine learning techniques. We have integrated machine learning with feature selection methods and have compared their performances to identify ...

A deep learning model (ALNet) for the diagnosis of acute leukaemia lineage using peripheral blood cell images.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVES: Morphological differentiation among blasts circulating in blood in acute leukaemia is challenging. Artificial intelligence decision support systems hold substantial promise as part of clinical practise in detecting haematol...

Identification of drug combinations on the basis of machine learning to maximize anti-aging effects.

PloS one
Aging is a multifactorial process that involves numerous genetic changes, so identifying anti-aging agents is quite challenging. Age-associated genetic factors must be better understood to search appropriately for anti-aging agents. We utilized an ag...

A Reliable Machine Learning Approach applied to Single-Cell Classification in Acute Myeloid Leukemia.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Machine Learning research applied to the medical field is increasing. However, few of the proposed approaches are actually deployed in clinical settings. One reason is that current methods may not be able to generalize on new unseen instances which d...