Non-small cell lung cancer (NSCLC) remains a major health challenge worldwide, mainly due to the lack of effective early diagnostic biomarkers. Exosome-related genes have recently emerged as potential diagnostic markers due to their roles in tumor pr...
Journal of the American Chemical Society
Oct 23, 2025
Aptamers are powerful synthetic recognition elements for biosensing, yet their application in complex biofluids, such as human serum, is critically limited by enzymatic degradation. To overcome this fundamental challenge, we introduce a novel analyti...
Primary pulmonary lung cancer is rare in dogs, and clinicians increasingly rely on advanced imaging for diagnosis and treatment planning. However, manual lesion segmentation can be time-consuming and subject to operator variability. This retrospectiv...
European journal of cancer (Oxford, England : 1990)
Oct 20, 2025
STUDY AIM: Early detection of distant metastases is crucial, but current imaging detects them only when radiographically visible. This study reported subvisual chest CT signals could serve as early biomarkers for impending lung metastasis before radi...
Metabolomics : Official journal of the Metabolomic Society
Oct 18, 2025
INTRODUCTION: The identification of unknown metabolites remains a major challenge in untargeted metabolomics using liquid chromatography-mass spectrometry (LC-MS). This process typically depends on comparing mass spectral or chromatographic data to r...
Visceral pleural invasion (VPI) is a critical prognostic factor in early-stage non-small-cell lung cancer (NSCLC), significantly affecting patient outcomes. Conventional computed tomography (CT) often fails to diagnose VPI accurately. This retrospect...
The tumor microenvironment (TME) is associated with tumor prognosis, immunotherapy response, and prognosis in patients. Here, we hypothesized that the entire TME in pathology image is associated with the survival time prediction. To address this hypo...
BACKGROUND: Gut microbiota (GM) predict responses to immune checkpoint inhibitors (ICIs) in patients with advanced lung cancer. However, its role in patients with locally advanced lung cancer undergoing chemoradiotherapy (CRT) combined with consolida...
Lung cancer continues to be one of the most widespread and deadly cancer diagnoses that affects humans worldwide. Early detection of lung cancer leads to decreased mortality rates; however, several challenges hinder the development and deployment of ...
Journal of the Egyptian National Cancer Institute
Oct 13, 2025
BACKGROUND: Computed tomography imaging, a non-invasive tool, is used around the globe by medical professionals to identify and diagnose lung cancer; a lethal disease with high rates of occurrence and mortality globally. Radiomics extracted from medi...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.