AIMC Topic: Lymphoma

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Deep learning-based overall survival prediction model in patients with rare cancer: a case study for primary central nervous system lymphoma.

International journal of computer assisted radiology and surgery
PURPOSE: Primary central nervous system lymphoma (PCNSL) is a rare, aggressive form of extranodal non-Hodgkin lymphoma. To predict the overall survival (OS) in advance is of utmost importance as it has the potential to aid clinical decision-making. T...

Evaluation of Semiautomatic and Deep Learning-Based Fully Automatic Segmentation Methods on [F]FDG PET/CT Images from Patients with Lymphoma: Influence on Tumor Characterization.

Journal of digital imaging
The objective is to assess the performance of seven semiautomatic and two fully automatic segmentation methods on [F]FDG PET/CT lymphoma images and evaluate their influence on tumor quantification. All lymphoma lesions identified in 65 whole-body [F]...

Deep learning of image-derived measures of body composition in pediatric, adolescent, and young adult lymphoma: association with late treatment effects.

European radiology
OBJECTIVES: The objective of this study was to translate a deep learning (DL) approach for semiautomated analysis of body composition (BC) measures from standard of care CT images to investigate the prognostic value of BC in pediatric, adolescent, an...

Development and validation of a machine learning algorithm for predicting diffuse midline glioma, H3 K27-altered, H3 K27 wild-type high-grade glioma, and primary CNS lymphoma of the brain midline in adults.

Journal of neurosurgery
OBJECTIVE: Preoperative diagnosis of diffuse midline glioma, H3 K27-altered (DMG-A) and midline high-grade glioma without H3 K27 alteration (DMG-W), as well as midline primary CNS lymphoma (PCNSL) in adults, is challenging but crucial. The aim of thi...

Further predictive value of lymphovascular invasion explored via supervised deep learning for lymph node metastases in breast cancer.

Human pathology
Lymphovascular invasion, specifically lymph-blood vessel invasion (LBVI), is a risk factor for metastases in breast invasive ductal carcinoma (IDC) and is routinely screened using hematoxylin-eosin histopathological images. However, routine reports o...

Deep learning radiomics of dual-modality ultrasound images for hierarchical diagnosis of unexplained cervical lymphadenopathy.

BMC medicine
BACKGROUND: Accurate diagnosis of unexplained cervical lymphadenopathy (CLA) using medical images heavily relies on the experience of radiologists, which is even worse for CLA patients in underdeveloped countries and regions, because of lack of exper...

A deep learning model combining multimodal radiomics, clinical and imaging features for differentiating ocular adnexal lymphoma from idiopathic orbital inflammation.

European radiology
OBJECTIVES: To evaluate the value of deep learning (DL) combining multimodal radiomics and clinical and imaging features for differentiating ocular adnexal lymphoma (OAL) from idiopathic orbital inflammation (IOI).

A content-based image retrieval system for the diagnosis of lymphoma using blood micrographs: An incorporation of deep learning with a traditional learning approach.

Computers in biology and medicine
Lymphomas, or cancers of the lymphatic system, account for around half of all blood cancers diagnosed each year. Lymphoma is a condition that is difficult to diagnose, and accurate diagnosis is critical for effective treatment. Manual microscopic ana...

Subtype classification of malignant lymphoma using immunohistochemical staining pattern.

International journal of computer assisted radiology and surgery
PURPOSE: For the image classification problem, the construction of appropriate training data is important for improving the generalization ability of the classifier in particular when the size of the training data is small. We propose a method that q...

Outcome-based multiobjective optimization of lymphoma radiation therapy plans.

The British journal of radiology
At its core, radiation therapy (RT) requires balancing therapeutic effects against risk of adverse events in cancer survivors. The radiation oncologist weighs numerous disease and patient-level factors when considering the expected risk-benefit ratio...