Activity observed in biological neural networks is determined by anatomical connectivity between cortical areas. The monkey frontoparietal network facilitates cognitive functions, but the organization of its connectivity is unknown. Here, a new conne...
Brain extraction (a.k.a. skull stripping) is a fundamental step in the neuroimaging pipeline as it can affect the accuracy of downstream preprocess such as image registration, tissue classification, etc. Most brain extraction tools have been designed...
As non-human primates, macaques have a close phylogenetic relationship to human beings and have been proven to be a valuable and widely used animal model in human neuroscience research. Accurate skull stripping (aka. brain extraction) of brain magnet...
Single-cell RNA sequencing (scRNA-seq) can characterize cell types and states through unsupervised clustering, but the ever increasing number of cells and batch effect impose computational challenges. We present DESC, an unsupervised deep embedding a...
Deep convolutional neural networks (CNNs) have certain structural, mechanistic, representational, and functional parallels with primate visual cortex and also many differences. However, perhaps some of the differences can be reconciled. This study de...
Reconstruction of accurate cortical surfaces without topological errors (i.e., handles and holes) from infant brain MR images is very important in early brain development studies. However, infant brain MR images typically suffer extremely low tissue ...
Recent studies suggest that deep Convolutional Neural Network (CNN) models show higher representational similarity, compared to any other existing object recognition models, with macaque inferior temporal (IT) cortical responses, human ventral stream...
Computational intelligence and neuroscience
Oct 18, 2018
Electrocorticogram (ECoG) is a well-known recording method for the less invasive brain machine interface (BMI). Our previous studies have succeeded in predicting muscle activities and arm trajectories from ECoG signals. Despite such successful studie...
IEEE transactions on bio-medical engineering
Sep 28, 2018
It is largely unknown whether there is functional role difference between cortical gyral and sulcal regions. Recent advancements in neuroimaging studies demonstrate clear difference of structural connection profiles in gyral and sulcal areas, suggest...
In this study, we evaluated the convolutional neural network (CNN) method for modeling V1 neurons of awake macaque monkeys in response to a large set of complex pattern stimuli. CNN models outperformed all the other baseline models, such as Gabor-bas...
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