AIMC Topic: Machine Learning

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System-level time computation and representation in the suprachiasmatic nucleus revealed by large-scale calcium imaging and machine learning.

Cell research
The suprachiasmatic nucleus (SCN) is the mammalian central circadian pacemaker with heterogeneous neurons acting in concert while each neuron harbors a self-sustained molecular clockwork. Nevertheless, how system-level SCN signals encode time of the ...

Conventional and machine learning-based risk scores for patients with early-stage hepatocellular carcinoma.

Clinical and molecular hepatology
BACKGROUND/AIMS: The performance of machine learning (ML) in predicting the outcomes of patients with hepatocellular carcinoma (HCC) remains uncertain. We aimed to develop risk scores using conventional methods and ML to categorize early-stage HCC pa...

Protocol to explain support vector machine predictions via exact Shapley value computation.

STAR protocols
Shapley values from cooperative game theory are adapted for explaining machine learning predictions. For large feature sets used in machine learning, Shapley values are approximated. We present a protocol for two techniques for explaining support vec...

Machine learning-assisted chromium speciation using a single-well ratiometric fluorescent nanoprobe.

Chemosphere
Chromium is widely recognized as a significant pollutant discharged into the environment by various industrial activities. The toxicity of this element is dependent on its oxidation state, making speciation analysis crucial for monitoring the quality...

Identification of shared potential diagnostic markers in asthma and depression through bioinformatics analysis and machine learning.

International immunopharmacology
BACKGROUND: There is mounting evidence that asthma might exacerbate depression. We sought to examine candidates for diagnostic genes in patients suffering from asthma and depression.

Fuzzy machine learning logic utilization on hormonal imbalance dataset.

Computers in biology and medicine
In this research work, a novel fuzzy data transformation technique has been proposed and applied to the hormonal imbalance dataset. Hormonal imbalance is ubiquitously found principally in females of reproductive age which ultimately leads to numerous...

Machine Learning Exploration of the Relationship Between Drugs and the Blood-Brain Barrier: Guiding Molecular Modification.

Pharmaceutical research
OBJECTIVE: This study aimed to improve the efficiency of pharmacotherapy for CNS diseases by optimizing the ability of drug molecules to penetrate the Blood-Brain Barrier (BBB).