AIMC Topic: Machine Learning

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Aging associated immunosenescence in rheumatoid arthritis identified by machine learning and single cell profiling.

Scientific reports Aug 23, 2025
Rheumatoid arthritis (RA) is increasingly prevalent among older adults, who often experience more severe symptoms and face significant treatment challenges. This study aims to identify specific genes associated with aging in RA and to analyze their i...
Immunosenescence Gene Regulatory Networks Female Arthritis, Rheumatoid Gene Expression Profiling Aged Gene Ontology Single-Cell Analysis Humans Aging Protein Interaction Maps Machine Learning Macrophages
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Multi-kernel inception-enhanced vision transformer for plant leaf disease recognition.

Scientific reports Aug 23, 2025
The timely and precise identification of diseases in plants is essential for efficient disease control and safeguarding of crops. Manual identification of diseases requires expert knowledge in the field, and finding people with domain knowledge is ch...
Algorithms Deep Learning Image Processing, Computer-Assisted Neural Networks, Computer Plant Leaves Machine Learning Crops, Agricultural Plant Diseases
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Discovery of CRISPR-Cas12a clades using a large language model.

Nature communications Aug 23, 2025
CRISPR-Cas systems revolutionize life science. Metagenomes contain millions of unknown Cas proteins. Traditional mining relies on protein sequence alignments. In this work, we employ an evolutionary scale language model (ESM) to learn the information...
Cryoelectron Microscopy Large Language Models Bacterial Proteins Endodeoxyribonucleases CRISPR-Associated Proteins Machine Learning Polymorphism, Single Nucleotide CRISPR-Cas Systems
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Developing a hybrid machine learning model to predict treatment time duration as a workflow regulation tool in public and private dental clinics.

Scientific reports Aug 23, 2025
This study aimed to design a desktop application that implements machine learning algorithms to predict dental treatment time durations, assess the accuracy of the model, and assess its clinical efficiency. The Python programming language was used to...
Machine Learning Software Algorithms Female Adult Male Humans Middle Aged Time Factors Workflow Dental Clinics
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Identification and analysis of the endoplasmic reticulum stress hub genes in sepsis-associated ARDS.

Scientific reports Aug 23, 2025
Acute respiratory distress syndrome (ARDS) is one of the most common and serious complications in the development of sepsis. Endoplasmic reticulum stress (ERS) plays an important role in the pathophysiologic process of sepsis-associated ARDS. The aim...
Gene Expression Regulation Endoplasmic Reticulum Stress Gene Expression Profiling Humans Sepsis Databases, Genetic Machine Learning ROC Curve Respiratory Distress Syndrome Gene Regulatory Networks Computational Biology
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Predicting acupuncture efficacy for neck pain based on functional connectivity features: a machine learning study.

Annals of medicine Aug 22, 2025
OBJECTIVE: To explore the mechanisms of acupuncture-induced neck pain relief and identify appropriate candidates using neuroimaging and machine learning techniques.
Neuroimaging Neck Pain Magnetic Resonance Imaging Pain Measurement Acupuncture Therapy Adult Male Middle Aged Treatment Outcome Support Vector Machine Longitudinal Studies Machine Learning Brain Female Humans
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Machine learning framework for investigating nano- and micro-scale particle diffusion in colonic mucus.

Journal of nanobiotechnology Aug 22, 2025
Biosimilar artificial mucus models that mimic native mucus facilitate efficient, lab-based drug diffusion studies, addressing the costly and challenging preclinical phase of drug development, especially for nano- and micro-scale particle-based coloni...
Machine Learning Swine Nanoparticles Particle Size Diffusion Drug Delivery Systems Animals Colon Polystyrenes Mucus Hydrogels Rheology
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Increasing pathogenic germline variant diagnosis rates in precision medicine: current best practices and future opportunities.

Human genomics Aug 22, 2025
The accurate diagnosis of pathogenic variants is essential for effective clinical decision making within precision medicine programs. Despite significant advances in both the quality and quantity of molecular patient data, diagnostic rates remain sub...
Precision Medicine Genetic Testing High-Throughput Nucleotide Sequencing Germ-Line Mutation Humans Machine Learning
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Research on the synergistic prediction of the suitable distribution and chemical components of Panax Notoginseng under the background of climate warming.

BMC plant biology Aug 22, 2025
Panax notoginseng is a well-known research species in China. The issue of continuous crop barriers has led to a reduction in suitable habitats in Wenshan. In the context of global warming, it is far from adequate to merely predict the suitability dis...
Global Warming China Climate Change Panax notoginseng Machine Learning Ecosystem
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Near viewing behaviors predict educational system in a machine learning model.

Scientific reports Aug 22, 2025
Intensive education systems are believed to contribute to high rates of myopia. This study examined whether near-viewing behaviors in college students differ based on their pre-college educational systems and whether these behaviors can be used to cl...
Humans Machine Learning Students Myopia Refractive Errors Adolescent Young Adult Adult Male
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