Neoantigens have emerged as ideal targets for personalized cancer immunotherapy. We depict the pan-cancer peptide atlas by comprehensively collecting immunopeptidomics from 531 samples across 14 cancer and 29 normal tissues, and identify 389,165 cano...
Pathogenic yeasts are an increasing concern in healthcare, with species like often displaying drug resistance and causing high mortality in immunocompromised patients. The need for rapid and accessible diagnostic methods for accurate yeast identific...
Malaria is a disease that can result in a variety of complications. Diagnosis is carried out by an optical microscope and depends on operator experience. The use of artificial intelligence to identify morphological patterns in erythrocytes would imp...
OBJECTIVE: This study aimed to develop a predictive model for secondary infections in patients with severe or critical COVID-19 by analyzing clinical characteristics and laboratory indicators.
Metabolomics : Official journal of the Metabolomic Society
May 21, 2025
INTRODUCTION: There are significant challenges remain in accurately categorizing the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients.
Rapid respiratory rate (RR) changes in older adults may indicate serious illness. Therefore, accurately estimating RR for cardiorespiratory fitness is essential. However, machine learning algorithm-related errors are unsuitable for medical decision-m...
A large body of research suggests that better-looking people are associated with various positive outcomes, an effect labeled the beauty premium. However, the vast majority of this evidence has been demonstrated in WEIRD (Western, Educated, Industria...
Hyperspectral imaging (HSI) and machine learning (ML) have been employed in the medical field for classifying highly infiltrative brain tumours. Although existing HSI databases of in vivo human brains are available, they present two main deficiencies...
The RAS/ERK pathway plays a central role in diagnosis and therapy for many cancers. ERK activity is highly dynamic within individual cells and drives cell proliferation, metabolism, and other processes through effector proteins including c-Myc, c-Fos...
Environmental geochemistry and health
May 21, 2025
Risk assessment of water quality plays a crucial role in sustainable management of water resource. However, evaluating drinking water quality risk for different types of water within the same framework is a challenging task. The Water Quality Index (...
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