AIMC Topic: Machine Learning

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Analyzing biological and artificial neural networks: challenges with opportunities for synergy?

Current opinion in neurobiology
Deep neural networks (DNNs) transform stimuli across multiple processing stages to produce representations that can be used to solve complex tasks, such as object recognition in images. However, a full understanding of how they achieve this remains e...

Machine Learning Approach for Determining the Formation of β-Lactam Antibiotic Complexes with Cyclodextrins Using Multispectral Analysis.

Molecules (Basel, Switzerland)
The problem of determining the formation of complexes of β-lactam antibiotics with cyclodextrins (CDs) and the interactions involved in this process were addressed by machine learning on multispectral images. Complexes of β-lactam antibiotics, includ...

A Highly Sensitive Pressure-Sensing Array for Blood Pressure Estimation Assisted by Machine-Learning Techniques.

Sensors (Basel, Switzerland)
This work describes the development of a pressure-sensing array for noninvasive continuous blood pulse-wave monitoring. The sensing elements comprise a conductive polymer film and interdigital electrodes patterned on a flexible Parylene C substrate. ...

Applications of artificial neural networks in health care organizational decision-making: A scoping review.

PloS one
Health care organizations are leveraging machine-learning techniques, such as artificial neural networks (ANN), to improve delivery of care at a reduced cost. Applications of ANN to diagnosis are well-known; however, ANN are increasingly used to info...

A Multi-Layer Gaussian Process for Motor Symptom Estimation in People With Parkinson's Disease.

IEEE transactions on bio-medical engineering
The assessment of Parkinson's disease (PD) poses a significant challenge, as it is influenced by various factors that lead to a complex and fluctuating symptom manifestation. Thus, a frequent and objective PD assessment is highly valuable for effecti...

Exploration of the nanomedicine-design space with high-throughput screening and machine learning.

Nature biomedical engineering
Only a tiny fraction of the nanomedicine-design space has been explored, owing to the structural complexity of nanomedicines and the lack of relevant high-throughput synthesis and analysis methods. Here, we report a methodology for determining struct...

ELM-MHC: An Improved MHC Identification Method with Extreme Learning Machine Algorithm.

Journal of proteome research
The major histocompatibility complex (MHC) is a term for all gene groups of a major histocompatibility antigen. It binds to peptide chains derived from pathogens and displays pathogens on the cell surface to facilitate T-cell recognition and perform ...

Noninvasive prediction of Blood Lactate through a machine learning-based approach.

Scientific reports
We hypothesized that blood lactate concentration([Lac]) is a function of cardiopulmonary variables, exercise intensity and some anthropometric elements during aerobic exercise. This investigation aimed to establish a mathematical model to estimate [L...

Importance of medical data preprocessing in predictive modeling and risk factor discovery for the frailty syndrome.

BMC medical informatics and decision making
BACKGROUND: Increasing life expectancy results in more elderly people struggling with age related diseases and functional conditions. This poses huge challenges towards establishing new approaches for maintaining health at a higher age. An important ...