AIMC Topic: Machine Learning

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Key Predictors of Generativity in Adulthood: A Machine Learning Analysis.

The journals of gerontology. Series B, Psychological sciences and social sciences
OBJECTIVES: This study aimed to explore a broad range of predictors of generativity in older adults. The study included over 60 predictors across multiple domains, including personality, daily functioning, socioeconomic factors, health status, and me...

Machine learning-based risk assessment for cardiovascular diseases in patients with chronic lung diseases.

Medicine
The association between chronic lung diseases (CLDs) and the risk of cardiovascular diseases (CVDs) has been extensively recognized. Nevertheless, conventional approaches for CVD risk evaluation cannot fully capture the risk factors (RFs) related to ...

Screening of mitochondrial-related biomarkers connected with immune infiltration for acute respiratory distress syndrome through WGCNA and machine learning.

Medicine
Septic acute respiratory distress syndrome (ARDS) is a complex and noteworthy type, but its molecular mechanism has not been fully elucidated. The aim is to explore specific biomarkers to diagnose sepsis-induced ARDS. Gene expression data of sepsis a...

Big data analytics and machine learning in hematology: Transformative insights, applications and challenges.

Medicine
The integration of big data analytics and machine learning (ML) into hematology has ushered in a new era of precision medicine, offering transformative insights into disease management. By leveraging vast and diverse datasets, including genomic profi...

Machine learning-based models for advanced fibrosis in non-alcoholic steatohepatitis patients: A cohort study.

World journal of gastroenterology
BACKGROUND: The global prevalence of non-alcoholic steatohepatitis (NASH) and its associated risk of adverse outcomes, particularly in patients with advanced liver fibrosis, underscores the importance of early and accurate diagnosis.

Electrocardiogram-based machine learning for risk stratification of patients with suspected acute coronary syndrome.

European heart journal
BACKGROUND AND AIMS: The importance of risk stratification in patients with chest pain extends beyond diagnosis and immediate treatment. This study sought to evaluate the prognostic value of electrocardiogram feature-based machine learning models to ...

GraphATC: advancing multilevel and multi-label anatomical therapeutic chemical classification via atom-level graph learning.

Briefings in bioinformatics
The accurate categorization of compounds within the anatomical therapeutic chemical (ATC) system is fundamental for drug development and fundamental research. Although this area has garnered significant research focus for over a decade, the majority ...

Carmna: classification and regression models for nitrogenase activity based on a pretrained large protein language model.

Briefings in bioinformatics
Nitrogen-fixing microorganisms play a critical role in the global nitrogen cycle by converting atmospheric nitrogen into ammonia through the action of nitrogenase (EC 1.18.6.1). In this study, we employed six machine learning algorithms to model the ...

Mutual-assistance learning for trustworthy biomarker discovery and disease prediction.

Briefings in bioinformatics
Integrating and analyzing multiple omics datasets, such as genomics, environmental influences, and imaging endophenotypes, has yielded an abundance of candidate biomarkers. However, translating such findings into beneficial clinical knowledge for dis...

Federated transfer learning with differential privacy for multi-omics survival analysis.

Briefings in bioinformatics
Multi-omics data often suffer from the "big $p$, small $n$" problem where the dimensionality of features is significantly larger than the sample size, making the integration of multi-omics data for survival analysis of a specific cancer particularly ...