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Magnetic Resonance Imaging

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Machine learning-based assessment of morphometric abnormalities distinguishes bipolar disorder and major depressive disorder.

Neuroradiology
INTRODUCTION: Bipolar disorder (BD) and major depressive disorder (MDD) have overlapping clinical presentations which may make it difficult for clinicians to distinguish them potentially resulting in misdiagnosis. This study combined structural MRI a...

PIDGN: An explainable multimodal deep learning framework for early prediction of Parkinson's disease.

Journal of neuroscience methods
BACKGROUND: Parkinson's disease (PD), the second most common neurodegenerative disease in the world, is usually not diagnosed until the later stages of the disease, when patients might have already missed the best treatment period. Therefore, more ef...

AI-based assessment of longitudinal multiple sclerosis MRI: Strengths and weaknesses in clinical practice.

European journal of radiology
OBJECTIVES: In Multiple Sclerosis (MS) cerebral MRI is essential for disease and treatment monitoring. For this purpose, software solutions are available to support the radiologist with image interpretation and reporting of follow up imaging. Aim of ...

Advancements in Frank's sign Identification using deep learning on 3D brain MRI.

Scientific reports
Frank's sign (FS) is a diagnostic marker associated with aging and various health conditions. Despite its clinical significance, there lacks a standardized method for its identification. This study aimed to develop a deep learning model for automated...

ds-FCRN: three-dimensional dual-stream fully convolutional residual networks and transformer-based global-local feature learning for brain age prediction.

Brain structure & function
The brain undergoes atrophy and cognitive decline with advancing age. The utilization of brain age prediction represents a pioneering methodology in the examination of brain aging. This study aims to develop a deep learning model with high predictive...

Incremental accumulation of linguistic context in artificial and biological neural networks.

Nature communications
Large Language Models (LLMs) have shown success in predicting neural signals associated with narrative processing, but their approach to integrating context over large timescales differs fundamentally from that of the human brain. In this study, we s...

VGX: VGG19-Based Gradient Explainer Interpretable Architecture for Brain Tumor Detection in Microscopy Magnetic Resonance Imaging (MMRI).

Microscopy research and technique
The development of deep learning algorithms has transformed medical image analysis, especially in brain tumor recognition. This research introduces a robust automatic microbrain tumor identification method utilizing the VGG16 deep learning model. Mic...

Automatic segmentation of MRI images for brain radiotherapy planning using deep ensemble learning.

Biomedical physics & engineering express
This study aimed to develop and evaluate an efficient method to automatically segment T1- and T2-weighted brain magnetic resonance imaging (MRI) images. We specifically compared the segmentation performance of individual convolutional neural network ...

Interpretable and integrative deep learning for discovering brain-behaviour associations.

Scientific reports
Recent advances highlight the limitations of classification strategies in machine learning that rely on a single data source for understanding, diagnosing and predicting psychiatric syndromes. Moreover, approaches based solely on clinician labels oft...

Improving quantification accuracy of a nuclear Overhauser enhancement signal at -1.6 ppm at 4.7 T using a machine learning approach.

Physics in medicine and biology
A new nuclear Overhauser enhancement (NOE)-mediated saturation transfer MRI signal at -1.6 ppm, potentially from choline phospholipids and termed NOE(-1.6), has been reported in biological tissues at high magnetic fields. This signal shows promise fo...