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Integrating physiological signals for enhanced sleep apnea diagnosis with SleepNet.

Scientific reports
Sleep apnea, a prevalent respiratory disorder, poses significant health risks, including cardiovascular complications and behavioral issues, if left untreated. Traditional diagnostic methods like polysomnography, although effective, are often expensi...

A comparative analysis of heterogeneity in lung cancer screening effectiveness in two randomised controlled trials.

Nature communications
Clinical trials demonstrate that screening can reduce lung cancer mortality by over 20%. However, lung cancer screening effectiveness (reduction in lung cancer specific mortality) may vary by personal risk-factors. Here we evaluate heterogeneity in l...

ROC Analysis of Biomarker Combinations in Fragile X Syndrome-Specific Clinical Trials: Evaluating Treatment Efficacy via Exploratory Biomarkers.

Translational psychiatry
Fragile X Syndrome (FXS) is a rare neurodevelopmental disorder caused by a trinucleotide repeat expansion on the 5' untranslated region of the FMR1 gene. FXS is characterized by intellectual disability, anxiety, sensory hypersensitivity, and difficul...

Evaluating the Feasibility of a Dyadic, Touch-Based Multimedia Tablet Intervention and Its Effects on the Caregiver-Patient Relationship Among Individuals With Mild Cognitive Impairment: Qualitative Triangulation Study.

JMIR aging
BACKGROUND: Approximately 20% of the global population is affected by mild cognitive impairment (MCI), with around 15% progressing to dementia within 2 years. Touch-based multimedia applications can support cognitive, social, and physical functioning...

DeePosit, an AI-based tool for detecting mouse urine and fecal depositions from thermal video clips of behavioral experiments.

eLife
In many mammals, including rodents, social interactions are often accompanied by active urination (micturition), which is considered a mechanism for spatial scent marking. Urine and fecal deposits contain a variety of chemosensory signals that convey...

Soft robotic gloves versus mirror therapy: a long-term comparative study on hand function and motor recovery in post-stroke rehabilitation.

Journal of rehabilitation medicine
OBJECTIVE: This study aimed to compare the long-term effects of soft robotic gloves (SRGs) and mirror therapy on hand function and motor recovery in post-stroke patients.

Explainable deep learning algorithm for distinguishing IVIG-Resistant Kawasaki disease in Shandong peninsula, China.

BMC pediatrics
BACKGROUND: Intravenous immunoglobulin (IVIG) resistance of Kawasaki disease (KD) patients have a heightened risk of coronary artery lesions. We aimed to explore the predictive factors of IVIG resistance of KD from Shandong Peninsula in China, and es...

A Machine Learning Algorithm With an Oversampling Technique in Limited Data Scenarios for the Prediction of Present and Future Restorative Treatment Need: Development and Validation Study.

JMIR medical informatics
BACKGROUND: Untreated dental caries is the most common health condition worldwide. Therefore, new strategies need to be developed to reduce the manifestations of dental caries.

The critical effects of self-management strategies on predicting cancer survivors' future quality of life and health status using machine learning techniques.

PloS one
Despite the significance of enhancing the quality of life (QoL) and overall health status (including physical, mental, social, and spiritual well-being) among individuals who have survived cancer, the existing prediction model for QoL and health stat...