AIMC Topic: Markov Chains

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An Application of Random Walk Resampling to Phylogenetic HMM Inference and Learning.

IEEE transactions on nanobioscience
Statistical resampling methods are widely used for confidence interval placement and as a data perturbation technique for statistical inference and learning. An important assumption of popular resampling methods such as the standard bootstrap is that...

GOMCL: a toolkit to cluster, evaluate, and extract non-redundant associations of Gene Ontology-based functions.

BMC bioinformatics
BACKGROUND: Functional enrichment of genes and pathways based on Gene Ontology (GO) has been widely used to describe the results of various -omics analyses. GO terms statistically overrepresented within a set of a large number of genes are typically ...

HMMPred: Accurate Prediction of DNA-Binding Proteins Based on HMM Profiles and XGBoost Feature Selection.

Computational and mathematical methods in medicine
Prediction of DNA-binding proteins (DBPs) has become a popular research topic in protein science due to its crucial role in all aspects of biological activities. Even though considerable efforts have been devoted to developing powerful computational ...

The Role and Promise of Artificial Intelligence in Medical Toxicology.

Journal of medical toxicology : official journal of the American College of Medical Toxicology
Artificial intelligence (AI) refers to machines or software that process information and interact with the world as understanding beings. Examples of AI in medicine include the automated reading of chest X-rays and the detection of heart dysrhythmias...

Graph embedding and unsupervised learning predict genomic sub-compartments from HiC chromatin interaction data.

Nature communications
Chromatin interaction studies can reveal how the genome is organized into spatially confined sub-compartments in the nucleus. However, accurately identifying sub-compartments from chromatin interaction data remains a challenge in computational biolog...

Resilient fault-tolerant anti-synchronization for stochastic delayed reaction-diffusion neural networks with semi-Markov jump parameters.

Neural networks : the official journal of the International Neural Network Society
This paper deals with the anti-synchronization issue for stochastic delayed reaction-diffusion neural networks subject to semi-Markov jump parameters. A resilient fault-tolerant controller is utilized to ensure the anti-synchronization in the presenc...

Patient selection for proton therapy: a radiobiological fuzzy Markov model incorporating robust plan analysis.

Physical and engineering sciences in medicine
While proton therapy can offer increased sparing of healthy tissue compared with X-ray therapy, it can be difficult to predict whether a benefit can be expected for an individual patient. Predictive modelling may aid in this respect. However, the pre...

Deep Learning of Markov Model-Based Machines for Determination of Better Treatment Option Decisions for Infertile Women.

Reproductive sciences (Thousand Oaks, Calif.)
In this technical article, we are proposing ideas, that we have been developing on how machine learning and deep learning techniques can potentially assist obstetricians/gynecologists in better clinical decision-making, using infertile women in their...

Cost-effectiveness of targeted screening for the identification of patients with atrial fibrillation: evaluation of a machine learning risk prediction algorithm.

Journal of medical economics
As many cases of atrial fibrillation (AF) are asymptomatic, patients often remain undiagnosed until complications (e.g. stroke) manifest. Risk-prediction algorithms may help to efficiently identify people with undiagnosed AF. However, the cost-effec...