AIMC Topic: Microbiota

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Microbiome and fragmentation pattern of blood cell-free DNA and fecal metagenome enhance colorectal cancer micro-dysbiosis and diagnosis analysis: a proof-of-concept study.

mSystems
Colorectal cancer (CRC) is the third most common cancer, and it can be prevented by performing early screening. As a hallmark of cancer, the human microbiome plays important roles in the occurrence and development of CRC. Recently, the blood microbio...

VTrans: A VAE-Based Pre-Trained Transformer Method for Microbiome Data Analysis.

Journal of computational biology : a journal of computational molecular cell biology
Predicting the survival outcomes and assessing the risk of patients play a pivotal role in comprehending the microbial composition across various stages of cancer. With the ongoing advancements in deep learning, it has been substantiated that deep le...

Recent advances in therapeutic probiotics: insights from human trials.

Clinical microbiology reviews
SUMMARYRecent advances in therapeutic probiotics have shown promising results across various health conditions, reflecting a growing understanding of the human microbiome's role in health and disease. However, comprehensive reviews integrating the di...

The inconsistent pathogenesis of endometriosis and adenomyosis: insights from endometrial metabolome and microbiome.

mSystems
UNLABELLED: Endometriosis (EM) and adenomyosis (AM) are interrelated gynecological disorders characterized by the aberrant presence of endometrial tissue and are frequently linked with chronic pelvic pain and infertility, yet their pathogenetic mecha...

Disturbance and stability dynamics in microbial communities for environmental biotechnology applications.

Current opinion in biotechnology
Microbial communities are corner stones of environmental biotechnology, driving essential processes such as waste degradation, pollutant removal, and nutrient cycling, all fundamental to industrial bioprocesses and sustainability. The structure and f...

Microbiome determinants of productivity in aquaculture of whiteleg shrimp.

Applied and environmental microbiology
UNLABELLED: Aquaculture holds immense promise for addressing the food needs of our growing global population. Yet, a quantitative understanding of the factors that control its efficiency and productivity has remained elusive. In this study, we addres...

Unique Microbial Characterisation of Oesophageal Squamous Cell Carcinoma Patients with Different Dietary Habits Based on Light Gradient Boosting Machine Learning Classifier.

Nutrients
: The microbiome plays an important role in cancer, but the relationship between dietary habits and the microbiota in oesophageal squamous cell carcinoma (ESCC) is not clear. The aim of this study is to explore the complex relationship between the mi...

Hydraulic and thermal performance trigger the deterministic assembly of water microbiomes: From biogeographical homogenization to machine learning model.

Water research
Water quality at the point of consumption has long been a health issue because of the potential for microbial ecology. However, research on water hydraulic performance remains in its infancy, and in particular, little is known about the effects of th...

Insight into endophytic microbiota-driven geographical and bioactive signatures toward a novel quality assessment model for Codonopsis Radix.

Plant physiology and biochemistry : PPB
Codonopsis Radix, a medicinal and dietary herb in traditional Chinese medicine, largely owes its pharmacological efficacy to both intrinsic phytochemistry and symbiotic interactions with plant-associated microbes. Here, we deciphered the geo-environm...

Definition of the microbial rare biosphere through unsupervised machine learning.

Communications biology
The microbial rare biosphere, composed of low-abundance microorganisms in a community, lacks a standardized delineation method for its definition. Currently, most studies rely on arbitrary thresholds to define the microbial rare biosphere (e.g., 0.1%...