AIMC Topic: Models, Cardiovascular

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Artificial intelligence model comparison for risk factor analysis of patent ductus arteriosus in nationwide very low birth weight infants cohort.

Scientific reports
Despite the many comorbidities and high mortality rate in preterm infants with patent ductus arteriosus (PDA), therapeutic strategies vary depending on the clinical setting, and most studies of the related risk factors are based on small sample popul...

A deep learning approach to identify and segment alpha-smooth muscle actin stress fiber positive cells.

Scientific reports
Cardiac fibrosis is a pathological process characterized by excessive tissue deposition, matrix remodeling, and tissue stiffening, which eventually leads to organ failure. On a cellular level, the development of fibrosis is associated with the activa...

A method of parameter estimation for cardiovascular hemodynamics based on deep learning and its application to personalize a reduced-order model.

International journal for numerical methods in biomedical engineering
Precise model personalization is a key step towards the application of cardiovascular physical models. In this manuscript, we propose to use deep learning (DL) to solve the parameter estimation problem in cardiovascular hemodynamics. Based on the con...

Machine Learning Models for Survival and Neurological Outcome Prediction of Out-of-Hospital Cardiac Arrest Patients.

BioMed research international
BACKGROUND: Out-of-hospital cardiac arrest (OHCA) is a major health problem worldwide, and neurologic injury remains the leading cause of morbidity and mortality among survivors of OHCA. The purpose of this study was to investigate whether a machine ...

Geometric and biomechanical modeling aided by machine learning improves the prediction of growth and rupture of small abdominal aortic aneurysms.

Scientific reports
It remains difficult to predict when which patients with abdominal aortic aneurysm (AAA) will require surgery. The aim was to study the accuracy of geometric and biomechanical analysis of small AAAs to predict reaching the threshold for surgery, diam...

Explainable machine-learning predictions for complications after pediatric congenital heart surgery.

Scientific reports
The quality of treatment and prognosis after pediatric congenital heart surgery remains unsatisfactory. A reliable prediction model for postoperative complications of congenital heart surgery patients is essential to enable prompt initiation of thera...

A clinical deep learning framework for continually learning from cardiac signals across diseases, time, modalities, and institutions.

Nature communications
Deep learning algorithms trained on instances that violate the assumption of being independent and identically distributed (i.i.d.) are known to experience destructive interference, a phenomenon characterized by a degradation in performance. Such a v...

Combined deep CNN-LSTM network-based multitasking learning architecture for noninvasive continuous blood pressure estimation using difference in ECG-PPG features.

Scientific reports
The pulse arrival time (PAT), the difference between the R-peak time of electrocardiogram (ECG) signal and the systolic peak of photoplethysmography (PPG) signal, is an indicator that enables noninvasive and continuous blood pressure estimation. Howe...

A new deep learning algorithm of 12-lead electrocardiogram for identifying atrial fibrillation during sinus rhythm.

Scientific reports
Atrial fibrillation (AF) is the most prevalent arrhythmia and is associated with increased morbidity and mortality. Its early detection is challenging because of the low detection yield of conventional methods. We aimed to develop a deep learning-bas...

Decoding empagliflozin's molecular mechanism of action in heart failure with preserved ejection fraction using artificial intelligence.

Scientific reports
The use of sodium-glucose co-transporter 2 inhibitors to treat heart failure with preserved ejection fraction (HFpEF) is under investigation in ongoing clinical trials, but the exact mechanism of action is unclear. Here we aimed to use artificial int...