AIMC Topic: Nanoparticles
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Delimiting the knowledge space and the design space of nanostructured lipid carriers through Artificial Intelligence tools.
International journal of pharmaceutics
Oct 26, 2018
Nanostructured lipid carriers (NLC) are biocompatible and biodegradable nanoscale systems with extensive application for controlled drug release. However, the development of optimal nanosystems along with a reproducible manufacturing process is still...
In vitro intestinal epithelium responses to titanium dioxide nanoparticles.
Food research international (Ottawa, Ont.)
Oct 12, 2018
Titanium dioxide (TiO) is enclosed in many consumer products including pharmaceuticals, cosmetics, and foods. TiO (E171) is daily ingested as mixed nano- and submicron-sized particles since it is approved as a white colorant in Europe in a wide varie...
Development of a new format of competitive immunochromatographic assay using secondary antibody-europium nanoparticle conjugates for ultrasensitive and quantitative determination of ochratoxin A.
Food chemistry
Sep 19, 2018
In this study, to enhance the sensitivity of conventional immunochromatographic assay (ICA) two strategies including using a high sensitive label and changing the assay format, were simultaneously applied to develop an ultrasensitive format of ICA. I...
Comparison of response surface methodology and artificial neural network to optimize novel ophthalmic flexible nano-liposomes: Characterization, evaluation, in vivo pharmacokinetics and molecular dynamics simulation.
Colloids and surfaces. B, Biointerfaces
Aug 23, 2018
To improve the topical delivery of pilocarpine hydrochloride (PN) to treat glaucoma, flexible nano-liposomes containing PN (PN-FLs) were prepared, optimized and characterized. Artificial neural network (ANN) and response surface methodology (RSM) wer...
Nanocomplexes composed of chitosan derivatives and β-Lactoglobulin as a carrier for anthocyanins: Preparation, stability and bioavailability in vitro.
Food research international (Ottawa, Ont.)
Aug 22, 2018
To improve sustained-release property, stability and bioavailability of anthocyanins (ACNs) in vitro, we fabricated the nanocomplexes with chitosan hydrochloride (CHC), carboxymethyl chitosan (CMC) and β-Lactoglobulin (β-Lg). Response surface methodo...
Convolutional neural networks automate detection for tracking of submicron-scale particles in 2D and 3D.
Proceedings of the National Academy of Sciences of the United States of America
Aug 22, 2018
Particle tracking is a powerful biophysical tool that requires conversion of large video files into position time series, i.e., traces of the species of interest for data analysis. Current tracking methods, based on a limited set of input parameters ...
Functional Nanoparticles-Coated Nanomechanical Sensor Arrays for Machine Learning-Based Quantitative Odor Analysis.
ACS sensors
Aug 15, 2018
A sensing signal obtained by measuring an odor usually contains varied information that reflects an origin of the odor itself, while an effective approach is required to reasonably analyze informative data to derive the desired information. Herein, w...
Cell-Like Micromotors.
Accounts of chemical research
Aug 3, 2018
In the past decade, versatile micro- and nanosized machines have emerged as active agents for large-scale detoxification, sensing, microfabrication, and many other promising applications. Micromachines have also been envisioned as the next advancemen...
A method for optical imaging and monitoring of the excretion of fluorescent nanocomposites from the body using artificial neural networks.
Nanomedicine : nanotechnology, biology, and medicine
Apr 12, 2018
In this study, a new approach to the implementation of optical imaging of fluorescent nanoparticles in a biological medium using artificial neural networks is proposed. The studies were carried out using new synthesized nanocomposites - nanometer gra...
Electron spin resonance spectroscopy for immunoassay using iron oxide nanoparticles as probe.
Analytical and bioanalytical chemistry
Dec 26, 2017
With the help of iron oxide nanoparticles, electron spin resonance spectroscopy (ESR) was applied to immunoassay. Iron oxide nanoparticles were used as the ESR probe in order to achieve an amplification of the signal resulting from the large amount o...
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