AIMC Topic: Nanoparticles
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Identification of nanoparticle infiltration in human breast milk: Chemical profiles and trajectory pathways.
Proceedings of the National Academy of Sciences of the United States of America
May 12, 2025
Breast milk is crucial for infant health, offering essential nutrients and immune protection. However, despite increasing exposure risks from nanoparticles (NPs), their potential infiltration into human breast milk remains poorly understood. This stu...
A potential new strategy for BC treatment: NPs containing solanine and evaluation of its anticancer and antimetastatic properties.
BMC cancer
May 12, 2025
Solanine has been shown to inhibit cancer by regulating the expression of apoptosis (Bax, Bcl-2) and metastasis (CDH-1, MMP2) genes in various cancer cell types. We synthesized optimized niosome NPs (NPs) with high solubility and capacity for solanin...
Machine learning-driven optical microfiltration device for improved nanoplastic sampling and detection in water systems.
Journal of hazardous materials
May 1, 2025
The rising presence of nanoplastics in water poses toxicity risks and long-term ecological and health impacts. Detecting nanoplastics remains challenging due to their small size, complex chemistry, and environmental interference. Traditional filtrati...
Debugging the dynamics of protein corona: Formation, composition, challenges, and applications at the nano-bio interface.
Advances in colloid and interface science
Apr 30, 2025
The intricate interplay between nanomaterials and the biological molecules has garnered considerable interest in understanding the dynamics of protein corona formation at the nano-bio interface. This review provides an in-depth exploration of protein...
Computational intelligence modeling and optimization of small molecule API solubility in supercritical solvent for production of drug nanoparticles.
Scientific reports
Apr 28, 2025
Artificial Intelligence (AI) is applied in this research for the analysis of a novel green method for production of nanomedicine. The method is based on supercritical solvent for production of drug nanoparticles in which the AI was used to estimate t...
Machine learning modeling and response surface methodology driven antioxidant and anticancer activities of chitosan nanoparticle-mediated extracts of Bacopa monnieri.
International journal of biological macromolecules
Apr 23, 2025
This study investigates the potential of chitosan nanoparticles (CNPs) in enhancing the bioavailability and efficacy of Bacopa monnieri extracts, known for their neuroprotective, antioxidant, and anticancer properties. Different concentrations of CNP...
Novel PVDF mixed matrix membranes incorporated with green synthesized magnesium oxide nanoparticles for enhanced dye removal: Optimization using RSM, SOLVER, and ANN approach.
Environmental research
Apr 16, 2025
The application of nanofiltration membrane technology for removing pollutant dyes from industrial wastewater represents a significant advance in environmental remediation. This research explores the development and performance evaluation of a novel P...
Sonopermeation combined with stroma normalization enables complete cure using nano-immunotherapy in murine breast tumors.
Journal of controlled release : official journal of the Controlled Release Society
Apr 14, 2025
Nano-immunotherapy shows great promise in improving patient outcomes, as seen in advanced triple-negative breast cancer, but it does not cure the disease, with median survival under two years. Therefore, understanding resistance mechanisms and develo...
Recent advances in cutaneous drug delivery by iontophoresis.
Expert opinion on drug delivery
Apr 13, 2025
INTRODUCTION: Iontophoresis has been extensively studied for topical and transdermal drug delivery to stimulate the absorption of molecules that would hardly pass through the outermost layer of the skin passively. Recent research has focused on its c...
The role of machine learning in predicting titanium dioxide nanoparticles induced pulmonary pathology using transcriptomic biomarkers.
Journal of hazardous materials
Apr 10, 2025
This study explores the application of machine learning (ML) in identifying transcriptomic changes associated with pulmonary pathologies induced by titanium dioxide nanoparticles (TiO-NPs). Such an approach significantly contributes to understanding ...
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