AIMC Topic: Neural Pathways

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Assessing functional connectivity across 3D tissue engineered axonal tracts using calcium fluorescence imaging.

Journal of neural engineering
OBJECTIVE: Micro-tissue engineered neural networks (micro-TENNs) are anatomically-inspired constructs designed to structurally and functionally emulate white matter pathways in the brain. These 3D neural networks feature long axonal tracts spanning d...

Structured networks support sparse traveling waves in rodent somatosensory cortex.

Proceedings of the National Academy of Sciences of the United States of America
Neurons responding to different whiskers are spatially intermixed in the superficial layer 2/3 (L2/3) of the rodent barrel cortex, where a single whisker deflection activates a sparse, distributed neuronal population that spans multiple cortical colu...

Transferring and generalizing deep-learning-based neural encoding models across subjects.

NeuroImage
Recent studies have shown the value of using deep learning models for mapping and characterizing how the brain represents and organizes information for natural vision. However, modeling the relationship between deep learning models and the brain (or ...

The role of phase shifts of sensory inputs in walking revealed by means of phase reduction.

Journal of computational neuroscience
Detailed neural network models of animal locomotion are important means to understand the underlying mechanisms that control the coordinated movement of individual limbs. Daun-Gruhn and Tóth, Journal of Computational Neuroscience 31(2), 43-60 (2011) ...

Resting-state functional connectivity predicts the ability to adapt arm reaching in a robot-mediated force field.

NeuroImage
Motor deficits are common outcomes of neurological conditions such as stroke. In order to design personalised motor rehabilitation programmes such as robot-assisted therapy, it would be advantageous to predict how a patient might respond to such trea...

Multi-Site Diagnostic Classification of Schizophrenia Using Discriminant Deep Learning with Functional Connectivity MRI.

EBioMedicine
BACKGROUND: A lack of a sufficiently large sample at single sites causes poor generalizability in automatic diagnosis classification of heterogeneous psychiatric disorders such as schizophrenia based on brain imaging scans. Advanced deep learning met...

Age-related changes in the ease of dynamical transitions in human brain activity.

Human brain mapping
Executive functions, a set of cognitive processes that enable flexible behavioral control, are known to decay with aging. Because such complex mental functions are considered to rely on the dynamic coordination of functionally different neural system...

Brain maps 4.0-Structure of the rat brain: An open access atlas with global nervous system nomenclature ontology and flatmaps.

The Journal of comparative neurology
The fourth edition (following editions in 1992, 1998, 2004) of Brain maps: structure of the rat brain is presented here as an open access internet resource for the neuroscience community. One new feature is a set of 10 hierarchical nomenclature table...

Prediction of activation patterns preceding hallucinations in patients with schizophrenia using machine learning with structured sparsity.

Human brain mapping
Despite significant progress in the field, the detection of fMRI signal changes during hallucinatory events remains difficult and time-consuming. This article first proposes a machine-learning algorithm to automatically identify resting-state fMRI pe...

Pseudoneglect in Visual Search: Behavioral Evidence and Connectional Constraints in Simulated Neural Circuitry.

eNeuro
Most people tend to bisect horizontal lines slightly to the left of their true center (pseudoneglect) and start visual search from left-sided items. This physiological leftward spatial bias may depend on hemispheric asymmetries in the organization of...