SIGNIFICANCE: High-resolution optical imaging at significant depths is challenging due to scattering, which impairs image quality in living matter with complex structures. We address the need for improved imaging techniques in deep tissues.
Alzheimer's disease (AD) is a primary degenerative brain disorder commonly found in the elderly, Mild cognitive impairment (MCI) can be considered a transitional stage from normal aging to Alzheimer's disease. Therefore, distinguishing between normal...
Schizophrenia is a complicated mental condition marked by disruptions in thought processes, perceptions, and emotional responses, which can cause severe impairment in everyday functioning. sMRI is a non-invasive neuroimaging technology that visualize...
BACKGROUND: Accurate brain tumor segmentation from MRI images is critical in the medical industry, directly impacts the efficacy of diagnostic and treatment plans. Accurate segmentation of tumor region can be challenging, especially when noise and ab...
Neurodegenerative diseases (NDs), characterized by progressive neuronal degeneration and manifesting in diverse forms such as memory loss and movement disorders, pose significant challenges due to their complex molecular mechanisms and heterogeneous ...
BACKGROUND: Neurological disorders, particularly Parkinson's Disease (PD), are serious and progressive conditions that significantly impact patients' motor functions and overall quality of life. Accurate and timely diagnosis is still crucial, but it ...
Detection of Alzheimer's Disease (AD) is critical for successful diagnosis and treatment, involving the common practice of screening for Mild Cognitive Impairment (MCI). However, the progressive nature of AD makes it challenging to identify its causa...
Brain age gap, the difference between estimated brain age and chronological age via magnetic resonance imaging, has emerged as a pivotal biomarker in the detection of brain abnormalities. While deep learning is accurate in estimating brain age, the a...
In recent years, artificial intelligence (AI) has become an increasingly prominent focus of medical research, significantly impacting epileptology as well. Studies on deep learning (DL) and machine learning (ML) - the core of AI - have explored their...
Given the relationship between hippocampal atrophy and cognitive impairment in various pathological conditions, hippocampus segmentation from MRI is an important task in neuroimaging. Manual segmentation, though considered the gold standard, is time-...