AIMC Topic: Neuroimaging

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Automated brain extraction of multisequence MRI using artificial neural networks.

Human brain mapping
Brain extraction is a critical preprocessing step in the analysis of neuroimaging studies conducted with magnetic resonance imaging (MRI) and influences the accuracy of downstream analyses. The majority of brain extraction algorithms are, however, op...

Learning-based single-step quantitative susceptibility mapping reconstruction without brain extraction.

NeuroImage
Quantitative susceptibility mapping (QSM) estimates the underlying tissue magnetic susceptibility from MRI gradient-echo phase signal and typically requires several processing steps. These steps involve phase unwrapping, brain volume extraction, back...

Characterizing Alzheimer's Disease With Image and Genetic Biomarkers Using Supervised Topic Models.

IEEE journal of biomedical and health informatics
Neuroimaging and genetic biomarkers have been widely studied from discriminative perspectives towards Alzheimer's disease (AD) classification, since neuroanatomical patterns and genetic variants are jointly critical indicators for AD diagnosis. Gener...

Automated lesion segmentation with BIANCA: Impact of population-level features, classification algorithm and locally adaptive thresholding.

NeuroImage
White matter hyperintensities (WMH) or white matter lesions exhibit high variability in their characteristics both at population- and subject-level, making their detection a challenging task. Population-level factors such as age, vascular risk factor...

Machine Learning and Brain Imaging: Opportunities and Challenges.

Trends in neurosciences
Machine learning approaches may provide ways to link brain activation patterns to behavior at an individual-subject level. Using a comparative performance analysis, Jollans and colleagues (Neuroimage, 2019) highlight in a recent paper key considerati...

Convolutional Neural Network for Automated FLAIR Lesion Segmentation on Clinical Brain MR Imaging.

AJNR. American journal of neuroradiology
BACKGROUND AND PURPOSE: Most brain lesions are characterized by hyperintense signal on FLAIR. We sought to develop an automated deep learning-based method for segmentation of abnormalities on FLAIR and volumetric quantification on clinical brain MRIs...

From pattern classification to stratification: towards conceptualizing the heterogeneity of Autism Spectrum Disorder.

Neuroscience and biobehavioral reviews
Pattern classification and stratification approaches have increasingly been used in research on Autism Spectrum Disorder (ASD) over the last ten years with the goal of translation towards clinical applicability. Here, we present an extensive scoping ...

Cortical graph neural network for AD and MCI diagnosis and transfer learning across populations.

NeuroImage. Clinical
Combining machine learning with neuroimaging data has a great potential for early diagnosis of mild cognitive impairment (MCI) and Alzheimer's disease (AD). However, it remains unclear how well the classifiers built on one population can predict MCI/...

F-FDG-PET-based radiomics features to distinguish primary central nervous system lymphoma from glioblastoma.

NeuroImage. Clinical
The differential diagnosis of primary central nervous system lymphoma from glioblastoma multiforme (GBM) is essential due to the difference in treatment strategies. This study retrospectively reviewed 77 patients (24 with lymphoma and 53 with GBM) to...