AIMC Topic: Neuroimaging

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Relational-Regularized Discriminative Sparse Learning for Alzheimer's Disease Diagnosis.

IEEE transactions on cybernetics
Accurate identification and understanding informative feature is important for early Alzheimer's disease (AD) prognosis and diagnosis. In this paper, we propose a novel discriminative sparse learning method with relational regularization to jointly p...

Using deep belief network modelling to characterize differences in brain morphometry in schizophrenia.

Scientific reports
Neuroimaging-based models contribute to increasing our understanding of schizophrenia pathophysiology and can reveal the underlying characteristics of this and other clinical conditions. However, the considerable variability in reported neuroimaging ...

Successful classification of cocaine dependence using brain imaging: a generalizable machine learning approach.

BMC bioinformatics
BACKGROUND: Neuroimaging studies have yielded significant advances in the understanding of neural processes relevant to the development and persistence of addiction. However, these advances have not explored extensively for diagnostic accuracy in hum...

Feature Selection Based on Iterative Canonical Correlation Analysis for Automatic Diagnosis of Parkinson's Disease.

Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Parkinson's disease (PD) is a major progressive neurodegenerative disorder. Accurate diagnosis of PD is crucial to control the symptoms appropriately. However, its clinical diagnosis mostly relies on the subjective judgment of physicians and the clin...

Multiclass Classification for the Differential Diagnosis on the ADHD Subtypes Using Recursive Feature Elimination and Hierarchical Extreme Learning Machine: Structural MRI Study.

PloS one
The classification of neuroimaging data for the diagnosis of certain brain diseases is one of the main research goals of the neuroscience and clinical communities. In this study, we performed multiclass classification using a hierarchical extreme lea...

Ten problems and solutions when predicting individual outcome from lesion site after stroke.

NeuroImage
In this paper, we consider solutions to ten of the challenges faced when trying to predict an individual's functional outcome after stroke on the basis of lesion site. A primary goal is to find lesion-outcome associations that are consistently observ...

Making use of longitudinal information in pattern recognition.

Human brain mapping
Longitudinal designs are widely used in medical studies as a means of observing within-subject changes over time in groups of subjects, thereby aiming to improve sensitivity for detecting disease effects. Paralleling an increased use of such studies ...

Longitudinal clinical score prediction in Alzheimer's disease with soft-split sparse regression based random forest.

Neurobiology of aging
Alzheimer's disease (AD) is an irreversible neurodegenerative disease and affects a large population in the world. Cognitive scores at multiple time points can be reliably used to evaluate the progression of the disease clinically. In recent studies,...

Robust Machine Learning-Based Correction on Automatic Segmentation of the Cerebellum and Brainstem.

PloS one
Automated segmentation is a useful method for studying large brain structures such as the cerebellum and brainstem. However, automated segmentation may lead to inaccuracy and/or undesirable boundary. The goal of the present study was to investigate w...

A hierarchical model for integrating unsupervised generative embedding and empirical Bayes.

Journal of neuroscience methods
BACKGROUND: Generative models of neuroimaging data, such as dynamic causal models (DCMs), are commonly used for inferring effective connectivity from individual subject data. Recently introduced "generative embedding" approaches have used DCM-based c...