AIMC Topic: Norepinephrine

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Dissecting the Catecholamines: How New Approaches Will Facilitate the Distinction between Noradrenergic and Dopaminergic Systems.

ACS chemical neuroscience Mar 28, 2019
To overcome the limitations of fast scan cyclic voltammetry (FSCV) to discriminate between catecholamines, we discuss new approaches to monitor the dynamics of these neurochemicals with high spatial, genetic, and temporal specificity.
Optogenetics Electrochemical Techniques Catecholamines Norepinephrine Dopamine Humans Machine Learning Animals
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Emotional arousal amplifies competitions across goal-relevant representation: A neurocomputational framework.

Cognition Mar 8, 2019
Emotional arousal often facilitates memory for some aspects of an event while impairing memory for other aspects of the same event. Across three experiments, we found that emotional arousal amplifies competition among goal-relevant representations, s...
Goals Memory Facial Recognition Pattern Recognition, Visual Norepinephrine Memory, Short-Term Models, Biological Attention Conditioning, Classical Humans Neural Networks, Computer Female Young Adult Adult Male Emotions
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Modelling PTSD diagnosis using sleep, memory, and adrenergic metabolites: An exploratory machine-learning study.

Human psychopharmacology Feb 22, 2019
OBJECTIVE: Features of posttraumatic stress disorder (PTSD) typically include sleep disturbances, impaired declarative memory, and hyperarousal. This study evaluated whether these combined features may accurately delineate pathophysiological changes ...
Cross-Sectional Studies Cohort Studies Stress Disorders, Post-Traumatic Sleep Wake Disorders Norepinephrine Sleep Memory Disorders Epinephrine Memory Machine Learning Female Young Adult Adult Humans
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Refractory collapse and severe burn: Think about acute adrenal insufficiency.

The American journal of emergency medicine Dec 29, 2017
INTRODUCTION: Adrenal insufficiency (AI) is a rare endocrine disorder, which can in its acute form be life-threatening in case of late diagnosis or treatment. The stress during a thermal burn can easily decompensate the AI. We report the case of an a...
Hydrocortisone Vasoconstrictor Agents Shock Adrenal Insufficiency Humans Emergency Service, Hospital Female Burns Middle Aged Norepinephrine Hemodynamics
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Utilization of machine learning for prediction of post-traumatic stress: a re-examination of cortisol in the prediction and pathways to non-remitting PTSD.

Translational psychiatry Mar 21, 2017
To date, studies of biological risk factors have revealed inconsistent relationships with subsequent post-traumatic stress disorder (PTSD). The inconsistent signal may reflect the use of data analytic tools that are ill equipped for modeling the comp...
Norepinephrine Hydrocortisone Saliva Lymphocytes Heart Rate Adrenocorticotropic Hormone Linear Models Urine Longitudinal Studies Blood Pressure Area Under Curve Emergency Service, Hospital Risk Assessment Stress Disorders, Post-Traumatic ROC Curve Support Vector Machine Female Wounds and Injuries Young Adult Psychological Trauma Humans Adult Receptors, Glucocorticoid Machine Learning Male Algorithms
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Optimal Vasopressin Initiation in Septic Shock: The OVISS Reinforcement Learning Study.

JAMA May 20, 2025
IMPORTANCE: Norepinephrine is the first-line vasopressor for patients with septic shock. When and whether a second agent, such as vasopressin, should be added is unknown.
Vasoconstrictor Agents Humans Critical Illness Female Electronic Health Records Datasets as Topic Vasopressins Aged Clinical Decision-Making Practice Guidelines as Topic Reinforcement Machine Learning Male Organ Dysfunction Scores Hospital Mortality Middle Aged Shock, Septic Observational Studies as Topic Norepinephrine
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A novel scheme for non-invasive drug delivery with a magnetically controlled drug delivering capsule endoscope.

Journal of controlled release : official journal of the Controlled Release Society May 10, 2025
There is a lack of effective means for precise drug delivery of gastrointestinal diseases. Herein we report a novel magnetically controlled drug delivering capsule endoscope (MDCE) to achieve precision drug delivery for gastrointestinal diseases. MDC...
Swine Norepinephrine Drug Liberation Capsule Endoscopy Capsule Endoscopes Drug Delivery Systems Animals
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Scale to predict risk for refractory septic shock based on a hybrid approach using machine learning and regression modeling.

Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias Feb 1, 2025
OBJECTIVE: To develop a scale to predict refractory septic shock (SS) based on clinical variables recorded during initial evaluations of patients.
Intensive Care Units Female Aged Male Humans Machine Learning Retrospective Studies Regression Analysis Emergency Service, Hospital Registries Norepinephrine Middle Aged Risk Assessment ROC Curve Shock, Septic
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[Esmolol improves clinical outcome and tissue oxygen metabolism in patients with septic shock through controlling heart rate].

Zhonghua wei zhong bing ji jiu yi xue Sep 1, 2015
OBJECTIVE: To investigate whether esmolol could improve clinical outcome and tissue oxygen metabolism by controlling heart rate (HR) in patients with septic shock.
Heart Rate Arterial Pressure Central Venous Pressure Oximetry Length of Stay Humans Shock, Septic Propanolamines Prospective Studies Oxygen Intensive Care Units Norepinephrine Stroke Volume Hemodynamics
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