AIMC Topic: Organs at Risk

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Cluster-Based Toxicity Estimation of Osteoradionecrosis Via Unsupervised Machine Learning: Moving Beyond Single Dose-Parameter Normal Tissue Complication Probability by Using Whole Dose-Volume Histograms for Cohort Risk Stratification.

International journal of radiation oncology, biology, physics
PURPOSE: Given the limitations of extant models for normal tissue complication probability estimation for osteoradionecrosis (ORN) of the mandible, the purpose of this study was to enrich statistical inference by exploiting structural properties of d...

A Prospective Study of Machine Learning-Assisted Radiation Therapy Planning for Patients Receiving 54 Gy to the Brain.

International journal of radiation oncology, biology, physics
PURPOSE: The capacity for machine learning (ML) to facilitate radiation therapy (RT) planning for primary brain tumors has not been described. We evaluated ML-assisted RT planning with regard to clinical acceptability, dosimetric outcomes, and planni...

Deep learning segmentation of organs-at-risk with integration into clinical workflow for pediatric brain radiotherapy.

Journal of applied clinical medical physics
PURPOSE: Radiation therapy (RT) of pediatric brain cancer is known to be associated with long-term neurocognitive deficits. Although target and organs-at-risk (OARs) are contoured as part of treatment planning, other structures linked to cognitive fu...

Deep learning for head and neck semi-supervised semantic segmentation.

Physics in medicine and biology
. Radiation therapy (RT) represents a prevalent therapeutic modality for head and neck (H&N) cancer. A crucial phase in RT planning involves the precise delineation of organs-at-risks (OARs), employing computed tomography (CT) scans. Nevertheless, th...

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Medical physics
BACKGROUND:: Efficient and accurate delineation of organs at risk (OARs) is a critical procedure for treatment planning and dose evaluation. Deep learning-based auto-segmentation of OARs has shown promising results and is increasingly being used in r...

Custom-Trained Deep Learning-Based Auto-Segmentation for Male Pelvic Iterative CBCT on C-Arm Linear Accelerators.

Practical radiation oncology
PURPOSE: The purpose of this investigation was to evaluate the clinical applicability of a commercial artificial intelligence-driven deep learning auto-segmentation (DLAS) tool on enhanced iterative cone beam computed tomography (iCBCT) acquisitions ...

Deep learning and atlas-based models to streamline the segmentation workflow of total marrow and lymphoid irradiation.

La Radiologia medica
PURPOSE: To improve the workflow of total marrow and lymphoid irradiation (TMLI) by enhancing the delineation of organs at risk (OARs) and clinical target volume (CTV) using deep learning (DL) and atlas-based (AB) segmentation models.

Clinical assessment of deep learning-based uncertainty maps in lung cancer segmentation.

Physics in medicine and biology
. Prior to radiation therapy planning, accurate delineation of gross tumour volume (GTVs) and organs at risk (OARs) is crucial. In the current clinical practice, tumour delineation is performed manually by radiation oncologists, which is time-consumi...

Gross failure rates and failure modes for a commercial AI-based auto-segmentation algorithm in head and neck cancer patients.

Journal of applied clinical medical physics
PURPOSE: Artificial intelligence (AI) based commercial software can be used to automatically delineate organs at risk (OAR), with potential for efficiency savings in the radiotherapy treatment planning pathway, and reduction of inter- and intra-obser...