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Organs at Risk

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Incorporating dosimetric features into the prediction of 3D VMAT dose distributions using deep convolutional neural network.

Physics in medicine and biology
An accurate prediction of achievable dose distribution on a patient specific basis would greatly improve IMRT/VMAT planning in both efficiency and quality. Recently machine learning techniques have been proposed for IMRT dose prediction based on pati...

Benefits of deep learning for delineation of organs at risk in head and neck cancer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
PURPOSE/OBJECTIVE: Precise delineation of organs at risk (OARs) in head and neck cancer (HNC) is necessary for accurate radiotherapy. Although guidelines exist, significant interobserver variability (IOV) remains. The aim was to validate a 3D convolu...

Shape constrained fully convolutional DenseNet with adversarial training for multiorgan segmentation on head and neck CT and low-field MR images.

Medical physics
PURPOSE: Image-guided radiotherapy provides images not only for patient positioning but also for online adaptive radiotherapy. Accurate delineation of organs-at-risk (OARs) on Head and Neck (H&N) CT and MR images is valuable to both initial treatment...

Stochastic frontier analysis as knowledge-based model to improve sparing of organs-at-risk for VMAT-treated prostate cancer.

Physics in medicine and biology
Stochastic frontier analysis (SFA) is used as a novel knowledge-based technique in order to develop a predictive model of dosimetric features from significant geometric parameters describing a patient morphology. 406 patients treated with VMAT for pr...

A convolutional neural network algorithm for automatic segmentation of head and neck organs at risk using deep lifelong learning.

Medical physics
PURPOSE: This study suggests a lifelong learning-based convolutional neural network (LL-CNN) algorithm as a superior alternative to single-task learning approaches for automatic segmentation of head and neck (OARs) organs at risk.

Dosimetric study on learning-based cone-beam CT correction in adaptive radiation therapy.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists
INTRODUCTION: Cone-beam CT (CBCT) image quality is important for its quantitative analysis in adaptive radiation therapy. However, due to severe artifacts, the CBCTs are primarily used for verifying patient setup only so far. We have developed a lear...

A modality-adaptive method for segmenting brain tumors and organs-at-risk in radiation therapy planning.

Medical image analysis
In this paper we present a method for simultaneously segmenting brain tumors and an extensive set of organs-at-risk for radiation therapy planning of glioblastomas. The method combines a contrast-adaptive generative model for whole-brain segmentation...

CT male pelvic organ segmentation using fully convolutional networks with boundary sensitive representation.

Medical image analysis
Accurate segmentation of the prostate and organs at risk (e.g., bladder and rectum) in CT images is a crucial step for radiation therapy in the treatment of prostate cancer. However, it is a very challenging task due to unclear boundaries, large intr...

Deep convolutional neural network for segmentation of thoracic organs-at-risk using cropped 3D images.

Medical physics
PURPOSE: Automatic segmentation of organs-at-risk (OARs) is a key step in radiation treatment planning to reduce human efforts and bias. Deep convolutional neural networks (DCNN) have shown great success in many medical image segmentation application...