Journal of orthopaedic surgery and research
May 30, 2025
BACKGROUND: Macrophage polarization exacerbates the pathological processes of osteoarthritis (OA). Astragalus membranaceus (AM) can repair chondrocytes and serve as a protective agent for OA. Therefore, the study intended to identify macrophage polar...
Osteoarthritis (OA) is a complex disorder driven by the combination of environmental and genetic factors. Given its high global prevalence and heterogeneity, developing effective and personalized treatment methods is crucial. This requires identifyin...
Osteoarthritis is a widespread chronic joint disease, becoming increasingly prevalent, particularly among individuals over the age of 45. This condition causes joint pain and dysfunction, significantly disrupting daily life. The objective of this stu...
Journal of shoulder and elbow surgery
Apr 22, 2025
BACKGROUND: The humeral head resection plane relies on the anatomic neck as a reference for shoulder arthroplasty planning and accurate intraoperative placement of the humeral component. However, osteophytes and deformity associated with osteoarthrit...
Osteoarthritis (OA) is a degenerative joint disease with significant clinical and societal impact. Traditional diagnostic methods, including subjective clinical assessments and imaging techniques such as X-rays and MRIs, are often limited in their ab...
Journal of orthopaedic surgery and research
Apr 17, 2025
BACKGROUND: Osteoarthritis (OA) is the leading cause of degenerative joint disease, with total joint replacement as the only definitive cure. However, no disease-modifying therapy is currently available. Inflammation and fibrosis in the infrapatellar...
Veterinary journal (London, England : 1997)
Apr 9, 2025
Decreased mobility is a clinical sign of degenerative joint disease (DJD) in cats, which is highly prevalent, with 61 % of cats aged six years or older showing radiographic evidence of DJD. Radiographs can reveal morphological changes and assess join...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Apr 8, 2025
Osteoarthritis (OA) and rheumatoid arthritis (RA) are the two most common rheumatic diseases worldwide, causing pain and disability. Both conditions are highly heterogeneous, and their onset occurs insidiously with non-specific symptoms, so they are ...
Arthritis & rheumatology (Hoboken, N.J.)
Mar 20, 2025
OBJECTIVE: Osteoarthritis (OA) is a widespread degenerative joint disease that causes a considerable socioeconomic burden. Despite progress in genetic and environmental insights, early diagnosis is still limited by the lack of evident symptoms during...
Machine learning can be applied to identify key genes associated with osteoarthritis (OA). This study aimed to explore the differential expression of necroptosis-related genes (NRGs) during the progression of OA, identify key gene modules strongly li...
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