AIMC Topic: Osteogenesis
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Cracking the Code: The Role of Peripheral Nervous System Signaling in Fracture Repair.
Current osteoporosis reports
Jan 18, 2024
PURPOSE OF REVIEW: The traditionally understated role of neural regulation in fracture healing is gaining prominence, as recent findings underscore the peripheral nervous system's critical contribution to bone repair. Indeed, it is becoming more evid...
Bioinformatic analysis of related immune cell infiltration and key genes in the progression of osteonecrosis of the femoral head.
Frontiers in immunology
Jan 11, 2024
OBJECTIVE: Osteonecrosis of the femoral head (ONFH) is a common orthopedic condition that will prompt joint dysfunction, significantly impacting patients' quality of life. However, the specific pathogenic mechanisms underlying this disease remain elu...
Automated Detection of the Thoracic Ossification of the Posterior Longitudinal Ligament Using Deep Learning and Plain Radiographs.
BioMed research international
Nov 27, 2023
Ossification of the ligaments progresses slowly in the initial stages, and most patients are unaware of the disease until obvious myelopathy symptoms appear. Consequently, treatment and clinical outcomes are not satisfactory. This study is aimed at d...
Robotic cochlear implantation in post-meningitis ossified cochlea.
American journal of otolaryngology
Oct 22, 2022
AIM: To report the experience of an image-guided and navigation-based robot arm as an assistive surgical tool for cochlear implantation in a case with a labyrinthitis ossificans.
Improved diagnostic performance of plain radiography for cervical ossification of the posterior longitudinal ligament using deep learning.
PloS one
Apr 27, 2022
BACKGROUND: A high false-negative rate has been reported for the diagnosis of ossification of the posterior longitudinal ligament (OPLL) using plain radiography. We investigated whether deep learning (DL) can improve the diagnostic performance of rad...
Robot-assisted cochlear implant surgery in a patient with partial ossification of the basal cochlear turn: A technical note.
Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
Mar 29, 2022
Machine learning-guided evolution of BMP-2 knuckle Epitope-Derived osteogenic peptides to target BMP receptor II.
Journal of drug targeting
May 1, 2020
Bone morphogenetic protein-2 (BMP-2) is a key regulator of bone formation, growth and regeneration, which contains a conformational wrist epitope and a linear knuckle epitope that are functionally responsible for the protein by mediating its interact...
Whey Protein Complexes with Green Tea Polyphenols: Antimicrobial, Osteoblast-Stimulatory, and Antioxidant Activities.
Cells, tissues, organs
Jan 24, 2019
Polyphenols are known for their antimicrobial activity, whilst both polyphenols and the globular protein β-lactoglobulin (bLG) are suggested to have antioxidant properties and promote cell proliferation. These are potentially useful properties for a ...
Ossification area localization in pediatric hand radiographs using deep neural networks for object detection.
PloS one
Nov 16, 2018
BACKGROUND: Detection of ossification areas of hand bones in X-ray images is an important task, e.g. as a preprocessing step in automated bone age estimation. Deep neural networks have emerged recently as de facto standard detection methods, but thei...
Inhibitory activity of linarin on osteoclastogenesis through receptor activator of nuclear factor κB ligand-induced NF-κB pathway.
Biochemical and biophysical research communications
Dec 18, 2017
Linarin, a natural flavonoid glycoside widely found in plants, has been reported to possess anti-inflammation, neuroprotection and osteogenic properties. However, its impact on osteoclast remains unclear. In the present study, the effects of linarin ...
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