AIMC Topic: Oxidoreductases

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Neuroprotective effects of the Phellinus linteus ethyl acetate extract against H2O2-induced apoptotic cell death of SK-N-MC cells.

Nutrition research (New York, N.Y.) Nov 11, 2015
Numerous studies have suggested that neuronal cells are protected against oxidative stress-induced cell damage by antioxidants, such as polyphenolic compounds. Phellinus linteus (PL) has traditionally been used to treat various symptoms in East Asian...
MAP Kinase Signaling System Fruiting Bodies, Fungal Phellinus Neuroprotective Agents Cell Line, Tumor Basidiomycota Apoptosis Medicine, Korean Traditional Antioxidants Neurons Brain Plant Extracts Nerve Tissue Proteins Oxidative Stress Oxidoreductases Solvents Republic of Korea Humans Acetates Polyphenols Ethnopharmacology Gene Expression Regulation, Enzymologic Biological Products Polysaccharides
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Multifactor dimensionality reduction analysis to elucidate the cross-talk between one-carbon and xenobiotic metabolic pathways in multi-disease models.

Molecular biology reports Feb 4, 2015
Putatively functional polymorphisms of one-carbon and xenobiotic metabolic pathways influence susceptibility for wide spectrum of diseases. The current study was aimed to explore gene-gene interactions among these two metabolic pathways in four disea...
Metabolic Networks and Pathways Factor Analysis, Statistical Parkinson Disease Sex Factors Datasets as Topic Coronary Artery Disease Lupus Erythematosus, Systemic Genetic Predisposition to Disease Carbon Polymorphism, Single Nucleotide Male Case-Control Studies Multifactor Dimensionality Reduction Female Breast Neoplasms Transferases Epistasis, Genetic Humans Xenobiotics Oxidoreductases Gene Expression Regulation
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CHCHD4 Oxidoreductase Activity: A Comprehensive Analysis of the Molecular, Functional, and Structural Properties of Its Redox-Regulated Substrates.

Molecules (Basel, Switzerland) May 10, 2025
The human CHCHD4 protein, which is a prototypical family member, carries a coiled-coil-helix-coiled-coil-helix motif that is stabilized by two disulfide bonds. Using its CPC sequence motif, CHCHD4 plays a key role in mitochondrial metabolism, cell su...
Models, Molecular Mitochondria Oxidation-Reduction Mitochondrial Proteins Mitochondrial Precursor Protein Import Complex Proteins Oxidoreductases Humans Substrate Specificity
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