Spray drying is commonly used to produce amorphous solid dispersions (ASD) to improve the bioperformance of poorly water-soluble drugs. In this study, imaging techniques such as focused ion beam-scanning electron microscopy (FIB-SEM) and X-ray microc...
Monitoring protein particles is increasingly emphasized in the development of biopharmaceuticals due to potential immunogenicity. Accurate quantitation of protein particles is complicated by silicone oil droplets, a common pharmaceutical component in...
Dynamic light scattering (DLS) is an essential technique used for assessing the size of the particles in suspension, covering the range from nanometers to microns. Although it has been very well established for quite some time, improvement can still ...
By combining metal nodes with organic linkers we can potentially synthesize millions of possible metal-organic frameworks (MOFs). The fact that we have so many materials opens many exciting avenues but also create new challenges. We simply have too m...
Identification of unknowns is a bottleneck for large-scale untargeted analyses like metabolomics or drug metabolite identification. Ion mobility-mass spectrometry (IM-MS) provides rapid two-dimensional separation of ions based on their mobility throu...
The stretchable hydrogels provide potential alternatives to bionic skins. However, skin simulation remains seriously challenging due to its complex nature, including mechanical property, protective effect, and sensory capability. Herein, conductive g...
This article reviews several categories of electronic skins (e-skins) for monitoring signals involved in human health. It covers advanced candidate materials, compositions, structures, and integrate strategies of e-skin, focusing on stretchable and w...
Lipid droplet (LD) accumulation, a key feature of foam cells, constitutes an attractive target for therapeutic intervention in atherosclerosis. However, despite advances in cellular imaging techniques, current noninvasive and quantitative methods hav...
Journal of colloid and interface science
Jan 7, 2020
Interfacial energy between sludge foulants and rough membrane surface critically determines adhesive fouling in membrane bioreactors (MBRs). As a current available method, the advanced extensive Derjaguin-Landau-Verwey-Overbeek (XDLVO) approach canno...
Caused by the tick-borne spirochete , Lyme disease (LD) is the most common vector-borne infectious disease in North America and Europe. Though timely diagnosis and treatment are effective in preventing disease progression, current tests are insensiti...