The results presented in this article demonstrate the potential of artificial intelligence tools for predicting the endpoint of the granulation process in high-speed mixer granulators of different scales from 25L to 600L. The combination of neurofuzz...
Enabling the paradigm of quality by design requires the ability to quantitatively correlate material properties and process variables to measureable product performance attributes. Conventional, quality-by-test methods for determining tablet breaking...
As of November 2014, the Korean Ministry of Environment (KME) has been forecasting the concentration of particulate matter with diameters ≤ 10 μm (PM) classified into four grades: low (PM ≤ 30 μg m), moderate (30 < PM ≤ 80 μg m), high (80 < PM ≤ 150 ...
This article presents an application of artificial neural network (ANN) modelling towards prediction of depth filter loading capacity for clarification of a monoclonal antibody (mAb) product during commercial manufacturing. The effect of operating pa...
A predictive model of a virgin coconut oil (VCO) nanoemulsion system for the topical delivery of copper peptide (an anti-aging compound) was developed using an artificial neural network (ANN) to investigate the factors that influence particle size. F...
SAR and QSAR in environmental research
Jun 22, 2016
The understanding of the mechanisms and interactions that occur when nanomaterials enter biological systems is important to improve their future use. The adsorption of proteins from biological fluids in a physiological environment to form a corona on...
Environmental science and pollution research international
Apr 4, 2016
Neural network (NN) models were evaluated for the prediction of suspended particulates with aerodynamic diameter less than 10-μm (PM10) concentrations. The model evaluation work considered the sequential hourly concentration time series of PM10, whic...
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Mar 15, 2016
In this study, a novel in-line measurement technique of the air temperature distribution during a granulation process using a conical fluidized bed was designed and built for the purpose of measuring the temperature under the Process Analytical Techn...
Small (Weinheim an der Bergstrasse, Germany)
Mar 10, 2016
Hydrogel composites that respond to stimuli can form the basis of new classes of biomimetic actuators and soft robotic components. Common latex microspheres can be assembled and patterned by AC electric fields within a soft thermoresponsive hydrogel....
A stable label-free amperometric immunosensor is presented based on gold nanoparticles and graphene oxide nanocomposites for detection of cardiac troponin-I in the early diagnosis of myocardial infarction. For designing of the sensing platform, first...
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