AIMC Topic: Phosphates

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A deep learning framework to predict binding preference of RNA constituents on protein surface.

Nature communications Oct 30, 2019
Protein-RNA interaction plays important roles in post-transcriptional regulation. However, the task of predicting these interactions given a protein structure is difficult. Here we show that, by leveraging a deep learning model NucleicNet, attributes...
RNA Phosphates Uracil RNA-Binding Proteins Area Under Curve RNA, Small Interfering Ribonuclease III Argonaute Proteins Cytosine Ribose Guanine Gene Knockdown Techniques Adenine Humans Animals Deep Learning ROC Curve Protein Binding Mice
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Unlocking the hidden talent of DNA: Unexpected catalytic activity for colorimetric assay of alkaline phosphatase.

Analytica chimica acta Dec 21, 2018
Carboxylic acids have been efficiently used to activate HO to form even more potent oxidant-peroxy acids through enzyme-catalyzed processes. By employing acetic acid as the activator, herein we report for the first time that cofactor-free DNA display...
Biocatalysis Enzyme Assays Benzidines Phosphates Acetates Humans Alkaline Phosphatase Hydrogen Peroxide Hydrolysis DNA
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Role of FGF23 in Pediatric Hypercalciuria.

BioMed research international Dec 31, 2017
BACKGROUND: This study explored the possible role of FGF23 in pediatric hypercalciuria.
Fibroblast Growth Factors Infant, Newborn Creatinine Male Humans Calcium Body Mass Index Hydrochlorothiazide Infant Child, Preschool Female Parathyroid Hormone Vitamin D Adolescent Child Hypercalciuria Phosphates Fibroblast Growth Factor-23 Glomerular Filtration Rate Calcium, Dietary
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Determination of Seminal Concentration of Fingolimod and Fingolimod-Phosphate in Multiple Sclerosis Patients Receiving Chronic Treatment With Fingolimod.

Clinical pharmacology in drug development Dec 19, 2017
The safety profile of fingolimod 0.5 mg, approved therapy for relapsing multiple sclerosis, is well established in clinical and real-world studies. As fingolimod is teratogenic in rats, it was considered important to assess the concentrations of fing...
Semen Multiple Sclerosis Phosphates Male Middle Aged Immunosuppressive Agents Fingolimod Hydrochloride Humans Adult
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Serum phosphate as an additional marker for initiating hemodialysis in patients with advanced chronic kidney disease.

Biomedical journal Jan 19, 2016
BACKGROUND: Reconsidering when to initiate renal replacement therapy (RRT) in patients with chronic kidney disease (CKD) has been emphasized recently. With evolving modern aged and diabetes-prone populations, conventional markers of uremia are not su...
Retrospective Studies Female Aged Male Humans Biomarkers Renal Insufficiency, Chronic Glomerular Filtration Rate Phosphates Middle Aged Renal Dialysis Cohort Studies
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[Effects of Soil Microbial Diversity on the Phosphate Fraction in the Rhizosphere of in the Yeyahu Wetland in Beijing, China].

Huan jing ke xue= Huanjing kexue Nov 8, 2017
In this research, microorganisms in rhizosphere/non-rhizosphere soils of in the Yeyahu Wetland were studied. A sequential extraction procedure was used to analyze the phosphorus (P) forms in the rhizosphere/non-rhizosphere soil with a variety of pla...
Wetlands Phosphates Soil Beijing Bacteria Soil Microbiology Rhizosphere RNA, Ribosomal, 16S Poaceae
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Metabolic acidosis of chronic kidney disease and subclinical cardiovascular disease markers: Friend or foe?

Medicine Nov 1, 2017
The effect of chronic metabolic acidosis (MA) on cardiovascular disease (CVD) in the setting of chronic kidney disease (CKD) is largely unknown. Therefore, we aimed to study this relationship in nondialysis CKD patients.This cross-sectional, single-c...
Triglycerides Acidosis Bicarbonates Vascular Calcification Ankle Brachial Index Carotid Intima-Media Thickness Phosphates Renal Insufficiency, Chronic Glomerular Filtration Rate Cholesterol Risk Factors Prospective Studies Aged Biomarkers Cross-Sectional Studies Humans Female Male Cardiovascular Diseases Middle Aged Logistic Models
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