The journal of physical chemistry letters
Nov 30, 2025
This study centers on corrole, an emerging photosensitizer with great application potential, and innovatively develops an intelligent machine learning-based screening strategy. Through integrating molecular descriptor generation, feature engineering,...
Physical chemistry chemical physics : PCCP
Nov 12, 2025
Fluoroquinolones (FQs) are a family of antibiotic drugs well-known for their high photochemical activity: upon UV-vis excitation FQs may produce singlet oxygen and/or lose the fluorine atom. Pterins (Ptrs) are a class of organic photosensitizers with...
Hematoporphyrin monomethyl ether-photodynamic therapy (HMME-PDT) is a safe and effective treatment for port-wine stain (PWS). Comprehensive methods for predicting HMME-PDT efficacy based on clinical factors are lacking. This study aims to develop and...
Multimodal phototheranostics utilizing single molecules offer a "one-and-done" approach, presenting a convenient and effective strategy for cancer therapy. However, therapies based on conventional photosensitizers often suffer from limitations such a...
Accurate diagnosis is essential for effective cancer treatment, particularly in peritoneal surface malignancies, where failure to detect metastatic lesions can mislead the treatment plan. This study assessed the diagnostic accuracy of staging laparos...
Drug-induced photosensitivity is a potential adverse event of many drugs and chemicals used across a wide range of specialties in clinical medicine. In the present study, we investigated the feasibility of predicting the photosensitising effects of d...
PURPOSE: Lower-grade gliomas typically exhibit 5-aminolevulinic acid (5-ALA)-induced fluorescence in only 20-30% of cases, a rate that can be increased by doubling the administered dose of 5-ALA. Fluorescence can depict anaplastic foci, which can be ...
According to the World Health Organization (WHO) and the International Agency for Research on Cancer (IARC), the number of cancer cases and deaths worldwide is predicted to nearly double by 2030, reaching 21.7 million cases and 13 million fatalities....
Photodiagnosis and photodynamic therapy
Jun 6, 2024
BACKGROUND: The treatment of oral leukoplakia (OLK) with aminolaevulinic acid photodynamic therapy (ALA-PDT) is widespread. Nonetheless, there is variation in efficacy. Therefore, this study constructed a model for predicting the short-term efficacy ...
Photodiagnosis and photodynamic therapy
Nov 9, 2023
BACKGROUND: To quantitatively evaluate the effectiveness of the Noise2Noise (N2N) model, a deep learning (DL)-based noise reduction algorithm, on enhanced depth imaging-optical coherence tomography (EDI-OCT) images with different noise levels.
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