AIMC Topic: Pituitary Gland

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ConsisTNet: a spatio-temporal approach for consistent anatomical localization in endoscopic pituitary surgery.

International journal of computer assisted radiology and surgery
PURPOSE: Automated localization of critical anatomical structures in endoscopic pituitary surgery is crucial for enhancing patient safety and surgical outcomes. While deep learning models have shown promise in this task, their predictions often suffe...

A deep learning approach to predict differentiation outcomes in hypothalamic-pituitary organoids.

Communications biology
We use three-dimensional culture systems of human pluripotent stem cells for differentiation into pituitary organoids. Three-dimensional culture is inherently characterized by its ability to induce heterogeneous cell populations, making it difficult ...

Pituitary MRI Radiomics Improves Diagnostic Performance of Growth Hormone Deficiency in Children Short Stature: A Multicenter Radiomics Study.

Academic radiology
RATIONALE AND OBJECTIVES: To develop an efficient machine-learning model using pituitary MRI radiomics and clinical data to differentiate growth hormone deficiency (GHD) from idiopathic short stature (ISS), making the diagnostic process more acceptab...

deepPGSegNet: MRI-based pituitary gland segmentation using deep learning.

Frontiers in endocrinology
INTRODUCTION: In clinical research on pituitary disorders, pituitary gland (PG) segmentation plays a pivotal role, which impacts the diagnosis and treatment of conditions such as endocrine dysfunctions and visual impairments. Manual segmentation, whi...

Thin-Slice Pituitary MRI with Deep Learning-based Reconstruction: Diagnostic Performance in a Postoperative Setting.

Radiology
Background Achieving high-spatial-resolution pituitary MRI is challenging because of the trade-off between image noise and spatial resolution. Deep learning-based MRI reconstruction enables image denoising with sharp edges and reduced artifacts, whic...

A machine learning model to precisely immunohistochemically classify pituitary adenoma subtypes with radiomics based on preoperative magnetic resonance imaging.

European journal of radiology
PURPOSE: The type of pituitary adenoma (PA) cannot be clearly recognized with preoperative magnetic resonance imaging (MRI) but can be classified with immunohistochemical staining after surgery. In this study, a model to precisely immunohistochemical...

Leptin Stimulates Prolactin mRNA Expression in the Goldfish Pituitary through a Combination of the PI3K/Akt/mTOR, MKK/pMAPK and MEK/ERK Signalling Pathways.

International journal of molecular sciences
Leptin actions at the pituitary level have been extensively investigated in mammalian species, but remain insufficiently characterized in lower vertebrates, especially in teleost fish. Prolactin (PRL) is a pituitary hormone of central importance to o...

Attention in surgical phase recognition for endoscopic pituitary surgery: Insights from real-world data.

Computers in biology and medicine
BACKGROUND AND OBJECTIVE: Surgical Phase Recognition systems are used to support the automated documentation of a procedure and to provide the surgical team with real-time feedback, potentially improving surgical outcome and reducing adverse events. ...

Feasibility of machine learning based predictive modelling of postoperative hyponatremia after pituitary surgery.

Pituitary
PURPOSE: Hyponatremia after pituitary surgery is a frequent finding with potential severe complications and the most common cause for readmission. Several studies have found parameters associated with postoperative hyponatremia, but no reliable speci...