AIMC Topic: Polymerase Chain Reaction

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Automated Classification and Cluster Visualization of Genotypes Derived from High Resolution Melt Curves.

PloS one
INTRODUCTION: High Resolution Melting (HRM) following PCR has been used to identify DNA genotypes. Fluorescent dyes bounded to double strand DNA lose their fluorescence with increasing temperature, yielding different signatures for different genotype...

Prediction of success for polymerase chain reactions using the Markov maximal order model and support vector machine.

Journal of theoretical biology
Polymerase chain reaction (PCR) is hailed as one of the monumental scientific techniques of the twentieth century, and has become a common and often indispensable technique in many areas. However, researchers still frequently find some DNA templates ...

Estimation of teaching-learning-based optimization primer design using regression analysis for different melting temperature calculations.

IEEE transactions on nanobioscience
Primers plays important role in polymerase chain reaction (PCR) experiments, thus it is necessary to select characteristic primers. Unfortunately, manual primer design manners are time-consuming and easy to get human negligence because many PCR const...

Using machine learning models to predict the impact of template mismatches on polymerase chain reaction assay performance.

Scientific reports
Molecular assays are critical tools for the diagnosis of infectious diseases. These assays have been extremely valuable during the COVID pandemic, used to guide both patient management and infection control strategies. Sustained transmission and unhi...

At the Mercy of the Artificial Intelligence Algorithm: Discrepant Polymerase Chain Reaction Results.

The Journal of infectious diseases
As pathogen molecular diagnostics technology develops, the software analysis of polymerase chain reaction sigmoidal curves, cycle threshold (Ct) values, and the limit of nucleic acid detection for that assay is not always available when reporting tes...

Research on automatic preprocessing equipment of salivary analyte for PCR inspection of coronavirus.

Science progress
Polymerase chain reaction (PCR) inspection of salivary analyte is performed by pretreatment, RNA extraction setup, RNA extraction, PCR setup, and the PCR process. However, the pretreatment process is conducted manually, and it is a bottleneck to the ...

Deep learning applications to combat the dissemination of COVID-19 disease: a review.

European review for medical and pharmacological sciences
Recent Coronavirus (COVID-19) is one of the respiratory diseases, and it is known as fast infectious ability. This dissemination can be decelerated by diagnosing and quarantining patients with COVID-19 at early stages, thereby saving numerous lives. ...