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Positron-Emission Tomography

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Ultra-Low-Dose F-Florbetaben Amyloid PET Imaging Using Deep Learning with Multi-Contrast MRI Inputs.

Radiology
Purpose To reduce radiotracer requirements for amyloid PET/MRI without sacrificing diagnostic quality by using deep learning methods. Materials and Methods Forty data sets from 39 patients (mean age ± standard deviation [SD], 67 years ± 8), including...

3D Auto-Context-Based Locality Adaptive Multi-Modality GANs for PET Synthesis.

IEEE transactions on medical imaging
Positron emission tomography (PET) has been substantially used recently. To minimize the potential health risk caused by the tracer radiation inherent to PET scans, it is of great interest to synthesize the high-quality PET image from the low-dose on...

A Deep Learning Model to Predict a Diagnosis of Alzheimer Disease by Using F-FDG PET of the Brain.

Radiology
Purpose To develop and validate a deep learning algorithm that predicts the final diagnosis of Alzheimer disease (AD), mild cognitive impairment, or neither at fluorine 18 (F) fluorodeoxyglucose (FDG) PET of the brain and compare its performance to t...

Iterative PET Image Reconstruction Using Convolutional Neural Network Representation.

IEEE transactions on medical imaging
PET image reconstruction is challenging due to the ill-poseness of the inverse problem and limited number of detected photons. Recently, the deep neural networks have been widely and successfully used in computer vision tasks and attracted growing in...

Machine learning identified an Alzheimer's disease-related FDG-PET pattern which is also expressed in Lewy body dementia and Parkinson's disease dementia.

Scientific reports
Utilizing the publicly available neuroimaging database enabled by Alzheimer's disease Neuroimaging Initiative (ADNI; http://adni.loni.usc.edu/ ), we have compared the performance of automated classification algorithms that differentiate AD vs. normal...

Synthesis of Patient-Specific Transmission Data for PET Attenuation Correction for PET/MRI Neuroimaging Using a Convolutional Neural Network.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Attenuation correction is a notable challenge associated with simultaneous PET/MRI, particularly in neuroimaging, where sharp boundaries between air and bone volumes exist. This challenge leads to concerns about the visual and, more specifically, qua...

Dixon-VIBE Deep Learning (DIVIDE) Pseudo-CT Synthesis for Pelvis PET/MR Attenuation Correction.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Whole-body attenuation correction (AC) is still challenging in combined PET/MR scanners. We describe Dixon-VIBE Deep Learning (DIVIDE), a deep-learning network that allows synthesizing pelvis pseudo-CT maps based only on the standard Dixon volumetric...

Reproducible evaluation of classification methods in Alzheimer's disease: Framework and application to MRI and PET data.

NeuroImage
A large number of papers have introduced novel machine learning and feature extraction methods for automatic classification of Alzheimer's disease (AD). However, while the vast majority of these works use the public dataset ADNI for evaluation, they ...

Convolutional Neural Networks for Neuroimaging in Parkinson's Disease: Is Preprocessing Needed?

International journal of neural systems
Spatial and intensity normalizations are nowadays a prerequisite for neuroimaging analysis. Influenced by voxel-wise and other univariate comparisons, where these corrections are key, they are commonly applied to any type of analysis and imaging moda...